introduction: recent studies have shown the presence of cl- channels in heart and liver mitochondrial membranes. in this work, we have characterized the functional profile of a cl- channel from rat brain mitochondria. methods: after removing and homogenizing the rat brain, the supernatant was separately centrifuged in msedigitonin, h2o and na2co3 and mitochondrial inner membrane vesicles were o...

background: dyslipidemia is the major risk factor for cardiovascular disease in world and herbal medicines play an important role in the treatment of dyslipidemia. there are a few studies of sour tea ( hibiscus sabdariffa l.) effects on human. thus, the aim of the present study was to evaluate the efficacy of sour tea consumption on the lipid profile in dyslipidemic subjects. methods: a randomi...

conclusions maximal and supra-maximal races induce a significant increase in lipid peroxidation and cause non-negligible inflammation and muscle damage. these effects were relatively related to the physical exercise type and the sportive specialty. results a significant increase in malondialdehyde (mda) concentrations was observed in ss and mdr after the vameval test and in ldr after the limite...

diabetes is a global health problem in the world. probiotic food has anti-diabetic property. the aim of this trial was to determine the effect of probiotic fermented milk (kefir) on glucose and lipid profile control in patients with type 2 diabetes mellitus.this randomized double-blind placebo-controlled clinical trial was conducted on 60 diabetic patients aged 35 to 65 years.patients were rand...

strychnos henningsii gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of southern africa. the antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. the extract decreased the blood glucose level, feed...

background: the mechanism of cadmium induced osteoporosis is not well understood, so in this study, we examined the toxicity of bone marrow mesenchymal stem cell (mscs) following treatment of rats with cdcl2 in drinking water, to revile the effect of this chemical on differentiation potential of mscs. methods: at the end of third passage, mscs were grown in the osteogenic medium for 21 days. to...

the association of obesity and other metabolic conditions with osteoarthritis is under debate; however, a strong link between metabolic disturbances is suggested to contribute to increased incidences and progression of osteoarthritis. we examined the association of metabolic syndrome and its components with the incidence of knee osteoarthritis in iranian population. a community-based study was ...

strenuous aerobic exercise is associated with oxidative stress and tissue damage. therefore, we have investigated the effects of exercise and eicosapentaenoic acid supplementation, with or without vitamin e, on the plasma levels of vitamin c, e and a, il-6, and glutathione peroxidase activity in basketball players. thirty four male basketball players, enrolled in the study. subjects received 2g...

background: studies have shown that zinc and selenium deficiency is common in nonalcoholic fatty liver disease (nafld). however, the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld are not clear enough. the aim of this study was to compare the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld prognos...

this study was carried out to evaluate how various amounts of nanozeolite decrease the effects of aflatoxins (af) on color and oxidative stability of the broiler thigh meat. three hundred and thirty six one-day-old ross 308 male broiler chickens were divided into six groups including a control group, which received diet without af and nanozeolite, and five treatment groups that received diet wi...