نتایج جستجو برای: limited systemic scleroderma
تعداد نتایج: 596253 فیلتر نتایج به سال:
Systemic sclerosis (scleroderma; SSc) is divided further into limited cutaneous disease and diffuse cutaneous disease on the basis of the extent of skin thickening. Limited disease is defi ned as skin thickening that only affects the extremities below the elbows and/or below the knees. Diffuse cutaneous disease is defi ned as skin thickening proximal to the elbows/or knees in addition to distal...
INTRODUCTION The aim of the study was to interrogate the genetic architecture and autoimmune pleiotropy of scleroderma susceptibility in the Australian population. METHODS We genotyped individuals from a well-characterized cohort of Australian scleroderma patients with the Immunochip, a custom array enriched for single nucleotide polymorphisms (SNPs) at immune loci. Controls were taken from t...
Background: Systematic scleroderma is a chronic autoimmune, complex and progressive disease that has many physical, psychological and social consequences. The purpose of this study was to investigate the effect of integrated psychotherapy with the orientation of four common factors on reducing image body anxiety as well as its two sub-scales (the dissatisfaction and embarrassment of the person ...
We report a case of fluoroscopy-guided intraarticular steroid injection for sternoclavicular joint (SCJ) arthritis caused by limited cutaneous systemic sclerosis (SSc). A 50-year-old woman diagnosed with limited cutaneous SSc presented with swelling and pain in the right SCJ. MRI revealed signs of inflammation consistent with right-sided sternoclavicular joint arthritis. After the failure of or...
Key words: systemic sclerosis; scleroderma renal crisis; to complain of arthralgia affecting mainly her wrists sine scleroderma; sine hypertension and small joints of the hands. For the last several months she had experienced difficulty in swallowing and anorexia with a resultant weight loss of 20 kg. Despite these symptoms, she did not seek medical
AIM To investigate T-cell activation, the percentage of peripheral T regulatory cells (Tregs), Th17 cells and the circulating cytokine profile in systemic sclerosis (SSc). METHODS We enrolled a total of 24 SSc patients and 16 healthy controls in the study and divided the patients as having diffuse cutaneous SSc (dcSSc, n = 13) or limited cutaneous SSc (lcSSc, n = 11). We performed a further s...
Difficulty in the diagnosis of the disease scleroderma may occur at the early stage prior to the development of obvious skin sclerosis. A presumptive diagnosis may be made if Raynaud's phenomenon is accompanied by a positive 'neck test', 'scleroderma' capillary changes in the nailfolds or antinuclear antibodies. Definitive diagnosis may have to be delayed for several years from the onset of Ray...
Although definitive answers are not yet forthcoming, understanding the mechanisms of fibrosis in scleroderma might improve the relative therapeutic vacuum now surrounding not only generalised scleroderma (systemic sclerosis (SSc)) but also the fibrosis of keloid formation, cirrhosis of the liver, pulmonary fibrosis, and atherosclerosis as well. Discussion here will include immune, vascular, and...
While a number of studies have shown short-term beneficial effects of therapeutic plasma exchange (TPE) for treating systemic scleroderma (SSc), there have been no reports on the very long-term usage of TPE as the sole systemic treatment intervention. We report the case of a male patient, originally diagnosed with limited systemic scleroderma (lcSSc) in early 1990, who has been undergoing regul...
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