TO THE EDITOR: We read the article by Tse et al. 1 with interest , which showed the usefulness of 12-item General Health Questionnaire (GHQ-12) as a reliable screening tool for psychiatric disorders in the patients with functional dyspepsia. Interesting studies were recently published showed anxiety to be linked to functional dyspepsia and especially postprandial distress syndrome, but not epig...

This study aims to determine whether the features of dyspepsia can discriminate a subgroup of patients who present with non-ulcer dyspepsia from other diagnostic categories. The following groups were studied: One hundred and thirteen patients with endoscopically confirmed non-ulcer dyspepsia in the absence of clinical, biochemical or radiological evidence of other gastrointestinal diseases or d...

BACKGROUND Helicobacter pylori eradication therapy is routinely used for treating patients with peptic ulcer disease. AIMS To assess the value of symptomatic response to H pylori eradication therapy as a marker of post-treatment H pylori status. PATIENTS AND METHODS One hundred and nine dyspeptic patients with active duodenal or gastric ulceration association with H pylori infection had the...

OBJECTIVES To verify whether symptoms reported by patients with uninvestigated dyspepsia might be helpful in either classifying functional from organic dyspepsia (1st experiment), or recognising which Helicobacter pylori infected patients may benefit from eradication therapy (2nd experiment). METHODS We compared the performance of artificial neural networks and linear discriminant analysis in...

Human Immunodeficiency Virus (HIV) infection predisposes to a multitude of opportunistic infections, many of them resulting in gastrointestinal symptoms. There were doubts about the pattern of the incidence of H.pylori in HIV infected patients: one group argues that the immunodeficiency allows the increased replication of the bacteria and in the other hand others argues that there is no inflamm...

Due to its prevalence, impact on quality-of-life and the associated significant health resource utilization, dyspepsia is a major healthcare concern. The available management strategies for uninvestigated dyspepsia include prompt endoscopy, the 'test-and-treat' strategy for Helicobacter pylori, and empiric antisecretory therapy. There is consensus that endoscopy should be reserved for patients ...