Cervical spondylotic myelopathy can result from degenerative cervical spondylosis, herniated disk material, osteophytes, redundant ligamentum flavum, or ossification of the posterior longitudinal ligament. Surgical intervention for multi-level myelopathy aims to decompress the spinal cord and maintain stability of the cervical spine. Laminoplasty was major surgical advancement as laminectomy re...

Spinal stenosis is caused by narrowing of the spinal canal or neural foramina producing root ischaemia and neurogenic claudication [1] . Stenosis of the spinal canal is most often caused by a combination of loss of disc space, osteophytes and a hypertrophic ligamentum flavum. Not all patients with narrowing develop symptoms. However, the narrowing may progress to cause compression of the spinal...

STUDY DESIGN A study of lumbar ligamentum flavum (LF). OBJECTIVE The aim of this study was to identify LF hypertrophy related microRNAs (miRNAs) expression profile and to investigate the role of miRNAs in the development of LF hypertrophy in lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA Although histologic and biologic literature on LF hypertrophy is available, the pathomechanism...

rare clinical entity and the majority of these conditions are thought to result from rupture of the epidural vascular network. Hemorrhagic lumbar synovial cysts (1) and a hematoma occurring from the ligamentum flavum (2) or from a lumbar facet joint (3) have been reported as rare types of epidural hematoma. We report here on the radiologic and surgical findings of a case of chronic nontraumatic...

Hypertrophy of ligamentum flavum (LF) contributes to lumbar spinal stenosis (LSS) and is caused mainly by fibrosis. Recent data indicate that miR-155 plays a crucial role in the pathogenesis of different fibrotic diseases. This study aimed to test the hypothesis that miR-155 exerts effects on LF thickness by regulating collagen expression. We found that LF thickness and the expression of collag...

Ankylosing spondylitis poses several anesthetic challenges ranging from difficult airway to neuraxial blockade. Limited cervical spine mobility, restricted opening of the temporomandibular joint, and cardiorespiratory compromise makes anesthesia preferred technique in these patients. However due ossification interspinous ligament ligamentum flavum, also syndesmophytes between adjacent vertebrae...

BACKGROUND Ligamentum flavum (LF) hypertrophy is a common cause of lumbar spinal stenosis and is thought to be degeneration-driven. Developmental spinal stenosis (DSS) is characterized by pre-existing narrowed spinal canals and is likely a developmental problem that occurs in childhood. In these cases, the LF may demonstrate different characteristics as compared to degeneration-driven stenosis....

Cervical cord compression in elderly patients is usually degenerative in origin. We report a case of cervical cord compression due to focal deposition of calcium pyrophosphate dihydrate (CPPD) crystals in the ligamentum flavum. A 76 year old woman presented with a 3 week history of severe neck pain associated with intermittent L’Hermitt’s type electric shock sensations down both arms. Over this...