A 60-year-old male presented with a solitary, asymptomatic, erythematous annular plaque on the medial portion of his right distal leg. Clinically, the lesion had central atrophy with peripheral hyperpigmentation, elevation and scaling (Figure 1). The differential diagnosis at clinical examination included: granuloma annulare, angular lichen planus, hypertrophic tinea corporis, and pigmented Bow...

We present a 74-year-old female patient who developed a pityriasis lichenoides chronica (PLC) during etanercept therapy. This association is not described in the literature and might be considered in the spectrum of cutaneous adverse reactions of etanercept.

introduction: oral lichen planus (olp) is a common mucocutanous disorder with unknown etiology. while current data suggest that oral lichen planus is a cell-mediated autoimmune disease, it might be associated to s+100, cd+4 and cd+8 cells. because of differential diagnosis of olp and oral lichenoid lesion (oll) is usually difficult this study was designed to compare any probable immunohistochem...

Abstract The introduction of immune checkpoint inhibitors for the treatment a wide variety malignancies has led to rise in cutaneous immune-related adverse events (irAEs), including autoimmune and autoinflammatory skin conditions, which typically present within first 16 weeks treatment—on average, 3.6 after drug initiation. Cutaneous irAEs occur approximately 8.7% patients receiving antiprogram...

LPP is one of the main causes of primary cicatricial alopecias. This study was performed for review of histo-pathological characteristics of LPP, and for the first time the density of hair follicles in vertical scalp biopsies was compared with healthy scalp biopsies. Vertically sectioned scalp 5mm punch biopsies of 44 cases of LPP were examined(H&E and Alcian blue) according to NAHRS criteria (...