To cite: Hamzelou S, Sadeghinia A, Allameh SF, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014204827 DESCRIPTION A 50-year-old man presented with a small solitary pink-to-skin coloured plaque of 1 year duration on his penile shaft. The surface of the plaque was verrucose and not inflamed (figure 1). The patient mentioned severe pruritus. He had recent ...

The aim of this study was to determine the expression intensity of PCNA and Ki-67 tissue antigens related to pathologically modified oral mucosa in OLR lesions, and to determine the reaction intensity of these antigens in individual clinical forms, i.e. lichen ruber planus (LRP) and lichen ruber erosivus (LRE) comparing the reaction intensity with the inflammation grade and the degree of hyperk...

Kamari is performing a clinical trial (KM001-AB1) evaluating the safety and efficacy of KM001, novel topical TRPV3 inhibitor, in patients with moderate to severe pruritus caused by LSC. cation channel highly expressed keratinocytes affecting proliferation, differentiation inflammation processes can be activated various distinctive triggers. It was implicated pathogenesis chronic related disease...

Hypertrichosis cubiti, also known as hairy elbows syndrome, is an uncommon form of localized congenital hypertrichosis in which an excessive amount of long, fine, lanugo-type hair is found on skin of normal texture and morphology. The hair growth follows a bilateral symmetrical distribution and affects the extensor surface of the distal third of the upper arms and the proximal region of the for...

Successful DNA isolation is a critical step in molecular studies of symbiotic fungi including plant pathogens, mycorrhizal fungi, endophytic fungi and lichen-forming fungi. Whereas standard isolation protocols are usually the straightforward approach if axenic cultures are available, it is problematic to isolate DNA from fungi that grow in intricate associations with some other organisms. If th...

Towards the end of the past century, IJnna and Besnier published their studies on histopathology of eczema (now often called "allergic eczematous contact-type dermatitis" a name coined by Sulzberger to distinguish this entity from atopic dermatitis and circumscribed lichen simplex). These descriptions are now classics and have been extensively quoted in most well-known textbooks of dermatology....

Methods Mrs. E.F a 30 years old woman, was followed up, since 2003, for a lupus erythematous chronicus. In 2010, she presented a painful cheilitis of the upper lip that gradually increases in volume. Clinical examination showed a scaly macrocheilitis, the rest of the clinical examination was within normal limits. The labial biopsy showed a dyskeratotic hyperkeratosis, keratotic plugs, a pseudo-...