Lichen planopilaris (LPP) is also known as lichen follicularis or follicular lichen planus. LPP is a cutaneous disorder selectively involving hair follicles with a lymphocytic inflammatory process that eventually destroys the follicles 1. LPP is more common in women (60% to 90% of the cases) than men 2. LPP is a disease of unknown etiology whose pathogenesis is poorly understood despite a suspe...

Introduction: Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress ...

Oral Lichen Planus is a chronic inflammatory disease of unknown etiology. Erosive/ ulcerative oral lichen planus is often a painful condition that tends to become malignant, urging appropriate therapy. Laser therapy has recently been suggested as a new treatment option without significant side effects. This article presents two cases of erosive/ ulcerative oral lichen planus, who had not receiv...

It has been suggested that infection with hepatitis C virus may be associated with the development of lichen planus and that geographical area may be an important factor affecting the relative risk. The present 2-centre, prospective, epidemiological study investigates this possible association in north west England. A total of 45 patients with classical and/or erosive mucous membrane lichen pla...

discussion the disappearance of olp might be due to immunosuppressive therapy following liver transplantation. further observations and studies are necessary to clarify the relationship between olp and pbc. case presentation we describe a case of oral lichen planus (olp) accompanied with pbc that resolved following liver transplantation 14 years later. this patient received immunosuppressive dr...

Background Lichen planus is classified as a common and chronic papulo – squamous disease. It has been associated with liver disease particularly hepatitis C virus (HCV) infection, in several studies. This study aimed to evaluate the controversial relationship between HCV infection and lichen planus. Patients and methods This was an analytical case-control study. The study included 60 patients w...

Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statis...

Lichen planus pigmentosus is a pigmentary disorder of unknown etiology, with diffuse hyperpigmentation of sun-exposed areas, more commonly seen in some ethnic and racial groups. We report an unusual case of lichen planus pigmentosus in a 40-year-old man with Fizpatrick type III skin that was present in a blaschkoid distribution on the trunk, a distribution that has been rarely reported. This un...

BACKGROUND DNA cytometry is a technique that allows densitometric analysis of nuclear DNA of cells and in this way the evaluation of DNA ploidy. OBJECTIVE The purpose of the present study was the evaluation of DNA ploidy in oral leukoplakia and oral lichen planus and correlation with histological dysplasia. METHODS We analyzed oral incisional biopsies from a group of 40 patients with oral l...

Oral lichen planus is a premalignant chronic inflammatory mucosal disorder with unknown etiology. It is a multifactorial disease and in addition to genetic background, infections, stress, drug reactions are suggested as risk factors. Helicobacter pylori which is involved in development of many gastrointestinal lesions may also be implicated in oral lichen planus induction. This is of clear impo...