47 year old male with history of alcoholic liver cirrhosis came in with severe bilateral lower extremity pain and new onset acute bilateral limb ischemia. Vitals at admission were stable and physical examination showed clear cut cool bilateral lower extremities below both ankle joints with all the 10 toes being black suggesting gangrene. Bilateral dorsalis pedis and Posterior tibial pulses were...

We present a case of a 21-year-old African-American female with no significant medical history, who presented to the emergency department with a one-week history of blurry and double vision. Ophthalmology evaluation revealed bilateral retinal artery occlusion. Further workup with imaging of the brain was consistent with an ischemic stroke. Hereditary hypercoagulable workup was unremarkable and ...

BACKGROUND AND OBJECTIVES Patients who have systemic lupus erythematosus (SLE) and manifest antiphospholipid antibodies (APA) are at increased risk for thrombosis; however, it is difficult to predict who will clot. This study tested the hypothesis that peak D-dimer level measured routinely during follow-up identifies whether a hypercoagulable state is developing and, therefore, the patient is a...

The quartic force field of SO3 was computed fully ab initio using coupled cluster (CCSD(T)) methods and basis sets of up to spdfgh quality. The effect of inner-shell correlation was taken into account. The addition of tight d functions is found to be essential for accurate geometries and harmonic frequencies. The equilibrium geometry and vibrational fundamentals are reproduced to within 0.0003 ...

BACKGROUND Although cardiovascular disease (CVD) is recognized as a leading cause of death in patients with systemic lupus erythematosus (SLE) in western countries, there is hardly any data regarding Indian subjects with SLE. AIMS To determine the incidence of cardiac abnormalities and vascular lesions at autopsy and to assess their contribution to the mortality in patients with SLE. SETTIN...

Systemic lupus erythematosus was originally described by a dermatologist (Kaposi, 1872). The cardiac manifestations of this disease were first noticed by Libman in 1911 and published with Sacks in 1924 (4 cases). Recognition of the full clinical picture and of the interrelationship of the various aspects of the disease was achieved by the Mt. Sinai group in the years 1923-1935 (see Baehr et al....

Letters " The AnAlgesic sTeplAdder-Missing rungs. " Editor, " On a long enough timeline, the survival rate for everyone drops to zero. " Risk is an inevitable aspect of medical care with recent studies illustrating the potential harm that can be done to patients using diclofenac with a cardiac history and codeine in paediatric patients. These studies apply in both cases to small subsets of each...