Materials and methods. 51 patients, who were ill with generalized peritonitis, went through a prospective randomized research. They were randomized on groups depending on the objective score SAPS (1984): 29 survived people (53%) and 22 people with favorable end (47%). Intensive care and surgical tactics standardized patients. Lactoferrin (LF) as modulator of systemic inflammatory response (SIR)...

A "Qi" feeling (a kind of comfortable sense) during and after acupuncture is one of the important determinants to decide quantity (trial number) of acupuncture stimulation. It has been reported that various autonomic responses were evoked when patients felt "Qi" and when acupuncture stimulation had significant effects on EEGs. However, quantitative relationships among acupuncture stimulation, E...

A "Qi" feeling (a kind of comfortable sense) during and after acupuncture is one of the important determinants to decide quantity (trial number) of acupuncture stimulation. It has been reported that various autonomic responses were evoked when patients felt "Qi" and when acupuncture stimulation had significant effects on EEGs. However, quantitative relationships among acupuncture stimulation, E...

Human papillomavirus (HPV) cause common warts, laryngeal papilloma and genital condylomata and might lead to development of cervical cancer. Lactoferrin (LF) is a member of the transferrin family, which has antiviral activity against HPV-16. LF is an important player in the defense against pathogenic microorganisms and has also been shown to have activity against several viruses including herpe...

Background: Lassa fever (LF) is an acute viral haemorrhagic disease endemic in Ondo State, Nigeria. This study aimed to determine the factors associated with mortality among confirmed LF cases. Methods: A cross sectional study design was used by conducting a retrospective review of the records of all patients who had been treated for LF at the Federal Medical Centre, Owo since 2017 till March 2...

We tested the hypotheses that TSP-1 participates in the initiation of remodeling of small muscular arteries in response to altered blood flow and that the N-terminal domain of TSP-1 (hepI) can reverse the pathological inward remodeling of resistance arteries from SHR.We measured (1) changes in gene/protein expression in MA of 6 week old WKY and SHR exposed to either increased (+ 100 %) or reduc...

Lethal factor (LF), a zinc-dependent protease of high specificity produced by Bacillus anthracis, is the effector component of the binary toxin that causes death in anthrax. New therapeutics targeting the toxin are required to reduce systemic anthrax-related fatalities. In particular, new insights into the LF catalytic mechanism will be useful for the development of LF inhibitors. We evaluated ...

Anthrax lethal factor (LF) is a Zn(+2)-dependent metalloprotease that cleaves several MAPK kinases and is responsible for the lethality of anthrax lethal toxin (LT). We observed that a recombinant LF (LF-HMA) which differs from wild type LF (LF-A) by the addition of two residues (His-Met) to the native Ala (A) terminus as a result of cloning manipulations has 3-fold lower potency toward culture...

STUDY DESIGN Cross-sectional study. PURPOSE To investigate the relationship between ligamentum flavum (LF) thickening and lumbar segmental instability and disc degeneration and facet joint osteoarthritis. OVERVIEW OF LITERATURE Posterior spinal structures, including LF thickness, play a major role in lumbar spinal canal stenosis pathogenesis. The cause of LF thickening is multifactorial and...

Fatty liver is prevalent in apolipoprotein B (apoB)-defective familial hypobetalipoproteinemia (FHBL). Similar to humans, mouse models of FHBL produced by gene targeting (apob(+/38.9)) manifest low plasma cholesterol and increased hepatic triglycerides (TG) even on a chow diet due to impaired hepatic VLDL-TG secretive capacity. Because apoB truncations shorter than apoB48 are expressed in the i...