Full-overlap U+U collisions provide significantly larger initial energy densities at comparable spatial deformation, and significantly larger deformation and volume at comparable energy density, than semi-central Au+Au collisions. We show quantitatively that this provides a long lever arm for studying the hydrodynamic behavior of elliptic flow in much larger and denser collision systems and the...

Traumatic posterior dislocation of the shoulder is frequently missed because of its rarity and the absence of characteristic symptoms. Several signs should be emphasised: an overlap of the humeral head and glenoid rim in a true anteroposterior view and the light-bulb sign in the anteroposterior view. To make an accurate and early diagnosis, use of multidirectional radiographs combined with comp...

Many biological motor molecules move within cells using stepsizes predictable from their structures. Myosin VI, however, has much larger and more broadly distributed stepsizes than those predicted from its short lever arms. We explain the discrepancy by monitoring Qdots and gold nanoparticles attached to the myosin-VI motor domains using high-sensitivity nanoimaging. The large stepsizes were at...

Dimeric myosin VI moves processively hand-over-hand along actin filaments. We have characterized the mechanism of this processive motion by measuring the impact of structural and chemical perturbations on single-molecule processivity. Processivity is maintained despite major alterations in lever arm structure, including replacement of light chain binding regions and elimination of the medial ta...

OBJECTIVE Vertebral distraction is routinely performed during anterior cervical discectomy and fusion (ACDF). Overdistraction can injure the facet joints and may cause postoperative neck pain consequently. The purpose of this study was to investigate the clinical relevance of distraction force during ACDF. METHODS This study included 24 consecutive patients with single level cervical disc dis...

The corner stone of the classical model after Huxley and Simmons, which has been serving as a basis for the theory of muscle contraction for already four decades, is supposition that a myosin head can reside only in several discrete states and irregularly jumps from one state to another. Until now, it has not been found a way to experimentally verify this supposition although confirmation or re...