Heavy metals are considered as the most important pollutants of the aquatic environment. In the present study, acute toxicity test was used for the determination of lethal toxicity of Nickel in adult fish, Channa gachua as the test organism. Toxicity test is most reliable for accessing the adverse effect of pollutants on aquatic life. The LC50 values were determined and observed that the values...

The REACH Regulation requires information on acute oral toxicity for substances produced or imported in quantities greater than one ton per year. When registering, animal testing should be used as last resort. The standard acute oral toxicity test requires use of animals. Therefore, the European Chemicals Agency examined whether alternative ways exist to generate information on acute oral toxic...

Cadmium nitrate Cd(NO(3))(2) (CdN) is commonly used in Ni-Cd battery factories. The possibility of accidental exposure to CdN is great. CdN is very soluble in water compared to other Cd compounds. Therefore, acute toxicity would be expected to be quick due to rapid absorption after exposure. However, the mechanisms of CdN toxicity have not been fully elucidated. We investigated the acute lethal...

Biotransformation and time-dependent toxicity of pyrene and fluorene, in the presence and absence of the biotransformation inhibitor 6-propylpiperonyl butyl diethylene glycol ether known as piperonyl butoxide (PBO), were investigated in Hyalella azteca. Toxicokinetics and biotransformation were determined in both short- and longterm experiments. For pyrene, the uptake rate coefficient (ku = 99 ...

Silver nanoparticles (AgNPs), owing to their unique physical and chemical properties, have become increasingly popular in consumer products. However, data on their potential biological effects on marine organisms, especially invertebrates, remain very limited. This proof of principle study reports the chronic sub-lethal toxicity of two coated AgNPs (oleic acid coated AgNPs and polyvinylpyrrolid...

We studied by the laboratory tests impact of most widespread pesticides (insecticide “Actor”, fungicide “Scooter”, herbicide “Titus-C”) in different concentrations (0,001–1000 mg/L) and water on main ecotoxicological indexes genetic vicaristic “western” “eastern” allospecies great ramshorn Planorbarius corneus s. lato. It was established, ranges toxic action these pollutants (mg/L) are followin...

Mondal P., Mollah A. R. and Rahman M. M. 2008. Study on the Acute Toxicity of Chlorocid 20 EC to Tubifex sp. Lamarck, 1816. J .Soil .Nature. 2(3): 20-25 Static bioassay tests were conducted to assess the acute toxicity of chlorocid 20 Emulsified Concentration (EC) to Tubifex sp. Lamarck, 1816 during March to August 2006 in the Zoological Garden at Carzon hall campas of the Dhaka University. Tub...

Lewis lung carcinoma and EMT6 sarcoma growing as solid tumors in mice caused a gradual increase in the susceptibility of the animals to lethal toxicity of endotoxins (lipopolysaccharides [LPS]). By day 15 following inoculation of the tumors, the 50% lethal dose of LPS, which in normal mice was approximately 400 micrograms, decreased to 2 micrograms for the sarcoma-bearing mice and 0.1 microgram...

LY303366 is a semisynthetic derivative of the echinocandin class. During preclinical studies, lethal toxicity was observed in DBA/2 mice pretreated with a cortisone acetate dose followed by treatment with LY303366 at doses ranging from 12.5 to 50 mg/kg of body weight/day given intraperitoneally (i.p.). In the cortisone-treated, uninfected controls, 90% given LY303366 at 50 mg/kg died. Deaths oc...

Methomyl is currently used as a toxicant for the attracticide BioAttract in cotton and vegetables in China. However, methomyl is highly toxic to non-target organisms and a more environmental friendly acceptable alternative is required. Larvae of three lepidopteran insects Helicoverpa armigera, Agrotis ipsilon and Spodoptera litura are important pests of these crops in China. In the present stud...