BACKGROUND The sole report of annual leptospirosis incidence in continental Africa of 75-102 cases per 100,000 population is from a study performed in August 2007 through September 2008 in the Kilimanjaro Region of Tanzania. To evaluate the stability of this estimate over time, we estimated the incidence of acute leptospirosis in Kilimanjaro Region, northern Tanzania for the time period 2012-20...

Record-breaking and devastating rainfall events have occurred in the past decade. Rain and floods are considered the main risk factors for leptospirosis and several outbreaks have been reported following extreme weather events. In such situations, one possible intervention to prevent leptospirosis cases in high-risk groups is the use of chemoprophylaxis. However, not enough evidence of its effe...

INTRODUCTION We report a case of severe leptospirosis that occurred during winter in Tokyo, the capital of Japan. Leptospirosis is endemic in tropical regions and extremely rare in the urban areas of Japan. Only six new cases were reported in Tokyo in 2014. Most leptospirosis cases reported in urban areas of Japan were a result of occupational hazards, and there is no previous report of leptosp...

Bacteria of the genus Leptospira can cause widespread and potentially lethal bacterial zoonosis called leptospirosis. Considered a neglected tropical zoonotic disease, leptospirosis was recognized as global public health problem due to its increasing prevalence in developing developed countries. This review focused on current knowledge leptospiral infection, classification, epidemiology, detect...

BACKGROUND Leptospirosis is one of the most important zoonosis in the tropics. Currently, specific laboratory diagnostic test for leptospirosis such as polymerase chain reaction (PCR) or direct culture cannot be applied at the primary care setting especially in the resource- limited countries. Therefore, clinical presentation and laboratory examination are still the primary diagnostic tools for...

This retrospective study aims to identify and describe the problems associated with the laboratory and clinical diagnosis of leptospirosis. A total of 4,813 patients with suspected leptospirosis from an area of the Czech Republic, with a total population of 1.15 million, were examined during the period 2002-2010. Our study included only 855 patients: 545 men (mean age 41.03 ± 19.24) and 310 wom...

were anicteric leptospirosis.1 Main presentation in our cases was Weil’s disease, so, it is difficult to draw conclusions from only two patients of anicteric leptospirosis. As far as the study of Elizabeth F Daher et al is concerned this study also had Jaundice in 94.5% patients out of total 201 patients.2 MAT is a highly specific test, though sensitivity is poor, whereas mildly raised transami...

BACKGROUND Thrombocytopenia is commonly observed in severe leptospirosis. However, previous studies on coagulation alterations during leptospirosis resulted in inconsistent conclusions. Some findings showed that the prominent levels of thrombocytopenia observed in severe leptospirosis did not reflect the occurrence of disseminated intravascular coagulation (DIC) syndrome, while the others reach...

Leptospirosis is one of the main re-emerging zoonotic diseases with a worldwide distribution, mainly in regions hot or tropical climates. It caused by spirochetal bacteria genus Leptospira, which, their pathogenic life forms, causes asymptomatic to severe infections humans and animals. Animal-to-human transmission occurs most frequently occupationally exposed groups travelers. However, leptospi...

INTRODUCTION Leptospirosis is a zoonotic disease, which has become a major public health threat in Sri Lanka. A majority of patients are farmers in rural endemic areas. The purpose of the present study is to describe the level of knowledge and frequencies of risky practices related to leptospirosis among a sample of rural school adolescents in Galgamuwa, Kurunegala district, a highly endemic ar...