نتایج جستجو برای: leptin receptor rene polymorphism

تعداد نتایج: 699261  

احمدپناه, جواد,

     In the current study, phylogenetic analysis and molecular evolution of the mammalian’s Leptin was investigated. Data was achieved and aligned by searching its genome database, while all examined mammals contained only a single copy of the Leptin. The nucleotide substitution rate of the sequences and molecular evolution of the Leptin were calculated by maximum likelihood and neighbor-joinin...

Journal: :Gut 2002
J Barrenetxe A C Villaro L Guembe I Pascual M Muñoz-Navas A Barber M P Lostao

BACKGROUND AND AIM Leptin, a hormone mainly produced by fat cells, acts primarily on the hypothalamus regulating energy expenditure and food intake. Leptin receptors are expressed in several tissues and the possible physiological role of leptin is being extensively investigated, with the result that important peripheral actions of the hormone in the organism are being discovered. Recent studies...

2002
J Barrenetxe M P Lostao

Background and aim: Leptin, a hormone mainly produced by fat cells, acts primarily on the hypothalamus regulating energy expenditure and food intake. Leptin receptors are expressed in several tissues and the possible physiological role of leptin is being extensively investigated, with the result that important peripheral actions of the hormone in the organism are being discovered. Recent studie...

Journal: :Reproduction 2008
Saveria Aquila Vittoria Rago Carmela Guido Ivan Casaburi Silvia Zupo Amalia Carpino

Several studies have recently investigated the role of leptin, the adipocyte-secreted hormone, in the growth and reproduction of rodents, humans, and domestic animals. The present study was designed to explore the expression of leptin and its receptor in pig spermatozoa. Successful Western blot evidenced a 16 kDa band for leptin and six isoforms, ranging from 120 to 40 kDa, for the leptin recep...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2006
Philippe G Cammisotto Diane Gingras Christian Renaud Emile Levy Moïse Bendayan

Leptin is a hormone secreted by the gastric mucosa into the lumen of the stomach. It is present in its intact form in the intestine where it regulates nutrient absorption and intestinal mucosa integrity. We have identified the binding protein that protects leptin from the harsh conditions of the gastric juice. Immunoprecipitations and Western blot analyses demonstrated that leptin is present in...

Journal: :Journal of lipid research 2001
N Kawaji A Yoshida T Motoyashiki T Morita H Ueki

An anti-leptin receptor polyclonal antibody (receptor antibody), as well as leptin, stimulated the release of free fatty acids from isolated mouse fat pads in a time-dependent manner. Following a 90-min incubation, maximal lipolysis was observed at 6 microg/ml receptor antibody and 0.1 nM leptin. The receptor antibody did not show any additive effect to the stimulation of lipolysis induced by l...

Journal: :Acta Universitatis Palackianae Olomucensis Facultatis Medicae 1999
D Stejskal J Bartek V Růzicka P Stejskal L Jedelský I Oral D Horalík M Zurek

Leptin receptors are supposed to have signal effects and are located in most tissues in the organism but we failed to find literary data on concentration (measurement) of leptin receptors in the system circulation. We examined by the method of randomized selection the group of 20 patients with manifested atherosclerosis in whom BMI was calculated. Then we analyzed concentration of leptin recept...

Journal: :international journal of reproductive biomedicine 0
shiva shahsavari zahra noormohammadi shohreh zare karizi

background: recurrent spontaneous abortion is one of the diseases that can lead to physical, psychological, and, economical problems for both individuals and society. recently a few numbers of genetic polymorphisms in kinase insert domain-containing receptor (kdr) gene are examined that can endanger the life of the fetus in pregnant women. objective: the risk of kdr gene polymorphisms was inves...

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