We demonstrated a switchable reflective lens based on choleteric liquid crystal (CLC) with a plano-convex shape. The plano-convex CLC lens was fabricated by assembling a planar substrate and a concave substrate. The reflective CLC lens exhibits wavelength selectivity and handedness sensitivity like the conventional CLC cell. The plano-convex CLC lens acts as a biconvex lens with the same curvat...

eye lens is composed of cells of only one type — lens fibre cells — which derive from a monolayer of undifferentiated epithelial cells covering the anterior surface of the lens. In the bulk of the lens, these cells are arranged in concentric sheets, much like the layers of an onion. In order to minimise light scatter in the lens, the fibre cells have to be precisely aligned. The scanning electr...

Sip1, a Smad-binding zinc-finger homeodomain transcription factor, has essential functions in embryonic development, but its role in individual tissues and the significance of its interaction with Smad proteins have not been fully characterized. In the lens lineage, Sip1 expression is activated after lens placode induction, and as the lens develops, the expression is localized in the lens epith...

In the mouse mutant dysgenetic lens (dyl) the lens vesicle fails to separate from the ectoderm, causing a fusion between the lens and the cornea. Lack of a proliferating anterior lens epithelium leads to absence of secondary lens fibers and a dysplastic, cataractic lens. We report the cloning of a gene, FoxE3, encoding a forkhead/winged helix transcription factor, which is expressed in the deve...

BACKGROUND & OBJECTIVES With increasing use of soft contact lenses the incidence of contact lens induced infections is also increasing. This study was aimed to assess the knowledge of new and existing contact lens users about the risk of microbial contamination associated with improper use and maintenance of contact lenses, type of microbial flora involved and their potential to cause ophthalmi...

The size of an organ must be tightly controlled so that it fits within an organism. The mammalian lens is a relatively simple organ composed of terminally differentiated, amitotic lens fiber cells capped on the anterior surface by a layer of immature, mitotic epithelial cells. The proliferation of lens epithelial cells fuels the growth of the lens, thus controling the size of the lens. We repor...

The homeobox gene Six3 regulates forebrain development. Here we show that Six3 is also crucial for lens formation. Conditional deletion of mouse Six3 in the presumptive lens ectoderm (PLE) disrupted lens formation. In the most severe cases, lens induction and specification were defective, and the lens placode and lens were absent. In Six3-mutant embryos, Pax6 was downregulated, and Sox2 was abs...

Cheng-Wei Qiu, Tie Jun Cui, and co-workers present an all-dielectric semispherical lens with functions in shaping 3D wave-propagation paths in article 1600022. The cover image shows principle of the 3D superresolution imaging system, which includes a semispherical magnifying meta-lens and a planar focusing lens. The semispherical lens magnifies signals of the objects located at the core of lens...

Please be advised that this information was generated on 2017-03-31 and may be subject to change.

Several stages in the lens determination process have been defined, though it is not known which gene products control these events. At mid-gastrula stages in Xenopus, ectoderm is transiently competent to respond to lens-inducing signals. Between late gastrula and neural tube stages, the presumptive lens ectoderm acquires a lens-forming bias, becomes specified to form lens and begins differenti...