BACKGROUND Platelet-rich plasma (PRP) has been used to augment tissue repair and regeneration after musculoskeletal injury. However, there is increasing clinical evidence that PRP does not show a consistent clinical effect. Purpose/Hypothesis: This study aimed to compare the effects of the following non-neutrophil-containing (leukocyte-poor) plasma fractions on human skeletal muscle myoblast (H...

This paper offers a novel algorithm to better design LEDs arrays for illumination systems. First, the illuminance distribution of LED arrays is studied through theoretical analysis. Second, we present the algorithm criterion and steps. And finally, we use computer to simulate and verify this method. The results show that the illumination uniformity is significantly affected by the spacing of ea...

Technology has become an essential part in every aspect of our lives. However the key to a successful implementation of a technology depends on the acceptance by the general public. In order to increase the acceptance various approaches can be applied. In this paper, we will examine the humanrobot emotional interaction by investigating the capabilities of a developed low-resolution RGB-LED disp...

White-light emitting diode lamps for general illumination can be realized by a combination of a blue light-emitting diode semiconductor die and phosphors. Newly developed oxynitride and nitride phosphors are promising candidates for this application because they have suitable excitation and emission wavelengths and stable optical properties in a high temperature environment. High brightness war...

The therapeutic potential of stem cells and nuclear cloning has led to renewed interest in classical models of regeneration. This longstanding problem is undergoing a renaissance spurred by the availability of new techniques that finally allow analysis on the cellular and molecular level.

The neonatal mouse heart has the remarkable capacity to regenerate lost myocardium within the first week of life. Neonatal cardiomyocytes re-express fetal genes that control cell proliferation after injury to promote regeneration. The loss of regenerative capacity of the heart one week after birth coincides with repression of a fetal transcriptional program coordinated by epigenetic regulators....

Activation of Shh signaling is known to be observed following injury of the peripheral nerves such as the sciatic nerve. However, the precise role of Shh signaling during peripheral nerve regeneration is not fully understood. The inferior alveolar nerve (IAN) is most commonly injured during oral surgery. Unlike the sciatic nerve, the IAN is isolated from other craniofacial tissues, as it reside...

PURPOSE To provide an overview of the methodologies involved in the field of hair cell regeneration. First, the author provides a tutorial on the biotechnological foundations of this field to assist the reader in the comprehension and interpretation of the research involved in hair cell regeneration. Next, the author presents a review of stem cell and gene therapy and provides a critical apprai...