The upstream interaction of twin premixed hydrogen-air flames in 2-D turbulence is studied using direct numerical simulations with detailed chemistry. The primary objective is to determine the effect of flame stretch on the overall burning rate during various stages of the interaction. Preferential diffusion effects are accounted for by varying the equivalence ratio from symmetric rich-rich to ...

The lean approach is an idealizing improvement approach that has an enormous impact in the field of Operations Management. The approach is basically very process oriented and there was less attention first for planning and control, this being the profession of dealing with all kind of non-ideal manufacturing and supply-chain restrictions. During the last years, however, planning and control hav...

Purpose: The aim of this research is to examine how lean has been implemented at geriatric care in a municipal department in Sweden, focusing on the experiences and challenges of the employees, together with the strengths and weaknesses of the lean philosophy. Design/methodology/approach: The primary method used was a case study with interviews and observations on spot, in combination with a li...

Alcohol- and obesity-related liver diseases often coexist. The hepatic lipidomics due to alcohol and obesity interaction is unknown. We characterized the hepatic lipidome due to 1) alcohol consumption in lean and obese mice and 2) obesity and alcohol interactions. In the French-Tsukamoto mouse model, intragastric alcohol or isocaloric dextrose were fed with either chow (lean) or high-fat, high-...

BACKGROUND/AIMS Leptin restores gonadotropic function in lean hypogonadotropic animals by an unknown mechanism. We aimed to test the hypothesis that restoration of gonadotropic function is a result of an upregulation of central acetylated melanocortin production. METHODS AND RESULTS Lean ovariectomised (OVX) ewes received intracerebroventricular (i.c.v.) infusions of leptin (or vehicle) for 3...

PURPOSE The purpose of this article is to discuss the current state of implementation of Lean production in health care. The study focuses on the definition of Lean in health care and implementation process, barriers, challenges, enablers, and outcomes of implementing Lean production methods in health care. DESIGN/METHODOLOGY/APPROACH A comprehensive search of the literature concerning the im...

Lean Manufacturing often simply referred to as Lean is a process management philosophy that aims to improve the way in which products are manufactured. It does this through identifying and removing waste and creating a smooth transition between stages in the production process. To a large extent, it relies on visual and simple mechanical aids to assist in improving manufacturing e ectiveness. H...

It has been widely investigated that the application of operations management techniques is not only based on technical factors, but it is mainly associated with organizational factors such as culture, previous policies and procedures, etc. A very good example of promisng operations practices is Lean Six Sigma (L6σ). The main research question for L6σ is related to its liabilities regarding its...

Covariate modeling is a key step in the analysis of clinical data and is essential for establishing dosing recommendations for specific populations, e.g., in obese individuals and children. So far, no systematic approach exists to leverage the knowledge inherent in physiologically based pharmacokinetic (PBPK) models in this context. We introduce (i) a novel approach to model interindividual var...

Many SMEs are implementing lean production in collaboration with a business support agency in order to improve their competitiveness. This research investigated whether improvement initiatives had the intended effect in some companies. A questionnaire was answered by employees in 26 SMEs. The result indicated experienced effect concerning leadership, communication and employee commitment, areas...