Cadmium is a known industrial pollutant which accumulates in the kidney and its exposure leads to the production of reactive oxygen species (ROS). The present study was carried out to evaluate the protective effects of Peucedanum grande against CdCl2 induced renal toxicity in Wistar rats. Wistar rats were subjected to oral pre-treatment of P. grande (60 and 120 mg/kg b.wt) against the renal tox...

BACKGROUND The greatest disadvantage in the presently available potent synthetic anti-inflammatory drugs lies in their toxicity and reappearance of symptoms after discontinuation. Hence, people are returning to the natural products with the hope of safety and security. Several species of Mikania have been reported to have anti-inflammatory properties. AIM The present study aims to assess the ...

Crataegus oxycantha popularly known as Hawthorn is widely distributed in northern hemisphere especially in Asia, Europe and parts of America. Howthorn consist of more than 200 species and several parts of the plant is traditionally used in the china and Europe. In India it is widely distributed in the temperate Himalayan regions and the different parts of plant is used for multiple health effec...

introduction: our previous studies showed that hydroalcoholic extract of leaf of vitis vinifera relaxes the phenylephrine-induced contraction in rat thoracic aorta. this effect was dependent on endothelial integrity and no-cgmp system. the vasorelaxant effect of extract was much lesser on kcl-induced contraction. we, therefore, postulated that k+ channels are involved. the main aim of the prese...

This study was carried in order to determine short-term (acute) and long-term(subchronic) effects of Melastomastrum capitatum leaf methanol extract in the management and treatment of certain diseases in traditional and complementary medicines  by many villages in Mambila Nigeria. Acute and subchronic toxicities were carried out in  accordance with the Organization for Economic Cooperation and D...

BACKGROUND & OBJECTIVES The monoaminergic systems which exert a modulatory role in memory processing, are disturbed in Alzheimer's disease (AD) and Moringa oleifera (MO) has been shown to exert its effect in CNS by altering the brain monoamines. The present study aims to see whether chronic oral treatment of ethanolic extract of MO leaves can alter the brain monoamines (norepinephrine, dopamine...

The effect of Pistacia lentiscus L. leaf extracts (aqueous, 30% ethanol and 70% ethanol) was studied on the rat isolated trachea. Pistacia lentiscus L. extracts induced a relaxation on basal tone and precontracted trachea. On the rat isolated trachea precontracted by acetylcholine 10M, Pistacia lenticus L. leaf extracts (aqueous, 30% ethanol and 70% ethanol) induced a relaxation. EC 50 values f...

BACKGROUND Rhododendron leaf extracts were previously found to exert antimicrobial activities against a range of Gram-positive bacteria. In this study, we investigated which of the extracts with these antimicrobial properties would be best suited for further exploitation. Specifically, the project aims to identify biologically active compounds that affect bacterial but not mammalian cells when ...