Long distance Marriage (LDM) adalah hubungan jarak jauh antara suami dan istri tidak tinggal bersama, bisa beda kota maupun negara. Di Kota Jayapura - Papua banyak ditemukan kasus Distance Marriage, yang meninggalkan istrinya demi bekerja dinas di Jayapura. karena termasuk salah satu wilayah mudah dalam hal mencari pekerjaan. Dinamika rela dengan serumah akan berdampak menimbulkan Disharmoni Ke...

This paper presents in a systematic way problems encountered in the construction of Lyapunov function candidates for descriptor systems. The solutions to some of the major difficulties in the application of Lyapunov’s direct method to descriptor systems are presented. Some new results regarding the extension of Lyapunov’s direct method tied to the construction of the Lyapunov functions are give...

Metachromatic leukodystrophy is a neurological disease of the lysosomal deposit that has significant impact given implications for neurodegenerative deterioration patient. Currently, there no treatment available reverses development characteristic and systemic symptoms. Objective. Carry out an updated bibliographic search on most critical advances in diagnosis LDM. A retrospective topic review ...

Background: Insulin downregulates GLUT4 by accelerating degradation in lysosomes. Results: Insulin through H2O2 production dissociates retromer from LDM membrane in a protein kinase CK2-dependent manner. Conclusion: Insulin switches GLUT4 traffic route toward lysosomes via retromer inhibition. Significance: This revealed a unique oxidative stress-mediated insulin signal cascade that regulates t...

The localized-density-matrix (LDM) method has been developed to calculate the excited state properties of very large systems containing thousands of atoms. It is particularly suitable for simulating the dynamic electronic processes in nanoscale materials, and has been applied to poly(p-phenylenevynelene) (PPV) aggregates and carbon nanotubes. Absorption spectra of PPVs and carbon nanotubes have...

In this paper, the Laplace Decomposition Method (LDM) employed to obtain approximate analytical solutions of the Klein-Gordon equation. The results show that the method converges rapidly and approximates the exact solution very accurately using only few iterates of the recursive scheme.

The Laplace decomposition method (LDM) has been implemented on integro-differential equations to calculate the analytical exact solutions. Obtained results show the effectiveness, reliability and convergence of the proposed method. It may be concluded that the proposed method is a powerful tool for solving the integro-differential equations and other wide class of mathematical problems.

Abstract: In this article, we propose a reliable combination of Homotopy analysis method (HAM) and Laplace decomposition method (LDM) to solve linear and nonlinear partial differential equations effectively with less computation. The proposed method is called homotopy analysis transform method (HATM). This study represents significant features of HATM and its capability of handling linear and n...

PURPOSE The cooverexpression of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) observed in many human tumors and their synergistic interaction in the transformation of cells make these receptors important targets for the development of new targeted therapeutics. Targeting of EGFR and HER2 simultaneously has been pursued as a strategy with which to po...

Purpose: Low dose metronomic (LDM) chemotherapy, combined with VEGF signaling pathway inhibitors, is a highly effective strategy to coordinately inhibit angiogenesis and tumor growth in many adult preclinical cancer models. We have tested the efficacies of daily oral LDM topotecan alone and in combination with pazopanib, a VEGF receptor inhibitor, in three pediatric extracranial solid tumor mou...