The late assembly (L) domain of retrovirus Gag, required in the final steps of budding for efficient exit from the host cell, is thought to mediate its function through interaction with unknown cellular factors. Here, we report the identification of the Nedd4-like family of E3 ubiquitin protein ligases as proteins that specifically interact with the Rous sarcoma virus (RSV) L domain in vitro an...

Nanotechnology A new technique for fragmentation of small metabolites combining nanoparticle assisted laser desorption/ionization (LDI)-MS and MS/MS is reported by Kun Qian et al. in their Research Article on page 11310.

We demonstrate program extraction by the Light Dialectica Interpretation (LDI) on a minimal logic proof of the classical existence of Fibonacci numbers. This semi-classical proof is available in MinLog’s library of examples. The term of Gödel’s T extracted by the LDI is, after strong normalization, exactly the usual recursive algorithm which defines the Fibonacci numbers (in pairs). This outcom...

Titania represents an important material that has wide applications. The bactericidal efficiency of TiO(2) has been shown to be dependent on the size of the nanoparticles, so it is important to be able to reliably estimate their dimensions. In this study, a stable TiO(2) cluster suspension is produced by the thermal solvent process, and ultrasmall clusters (<1 nm) with different sizes are obtai...

This paper describes a new, simple, and sensitive method for detecting two fluoroquinolones: enrofloxacin and its metabolite ciprofloxacin, which are widely used as drugs for humans and animals. We utilized gold nanoparticles (AuNPs) and laser desorption/ionization time-of-flight (LDI-TOF) mass spectrometry (MS) with a matrix-free format. An antibody for the drug was immobilized on a chip based...

We present an efficient algorithm to perform approximate offsetting operations on geometric models using GPUs. Our approach approximates the boundary of an object with point samples and computes the offset by merging the balls centered at these points. The underlying approach uses Layered Depth Images (LDI) to organize the samples into structured points and performs parallel computations using ...

Representing Layered Depth Images (LDI) as 3D texture can be used to approximate complex, arbitrarily shaped volumes on graphics hardware. Based on this concept, a number of real-time applications such as collision detection or 3D clipping against multiple volumes can be implemented efficiently using programmable hardware. One major drawback of this image-based representation is the high video ...

In this paper it is shown that zero-input overflow limit cycles can be suppressed in a class of lossless digital integrator (LDI) all-pass filters, namely, that introduced in [1]. This holds for any filter order, provided that saturation overflow characteristics are used at the input of each delay and for certain restrictions for the multiplier values. The results are shown to apply also to los...

During the course of a study on the clustering of W-Se and W-S mixtures in the gas phase using laser desorption ionization (LDI) mass spectrometry, we observed several anionic W-O clusters. Three distinct species, W(6)O(19)(-), W(13)O(29)(-), and W(14)O(32)(-), stand out as intense peaks in the regular mass spectral pattern of tungsten oxide clusters suggesting unusual stabilities for them. Mor...

This paper describes a novel technique to analyze the effects of supply voltage noise on circuit delay for nanometer VLSI circuits. Scattering parameters are used to analyze the power supply noise and to reduce runtime and memory usage. The interconnections of the power grid are modeled by RLC passive elements, constant voltage and time-varying current sources. A fast and accurate MOS modeling ...