While it has been expected that X-ray laser will be widely applied to biomedical studies, this has not been achieved to date and its biological effects such as DNA damage have not been evaluated. As a first step for its biological application, we developed a culture cell irradiation system, particularly designed for a plasma-driven soft X-ray laser pulse, to investigate whether the soft X-ray l...

OBJECTIVES X-ray computed tomography (CT) using phase contrast can provide images with greatly enhanced soft-tissue contrast in comparison to conventional attenuation-based CT. We report on the first scan of a human specimen recorded with a phase-contrast CT system based on an x-ray grating interferometer and a conventional x-ray tube source. Feasibility and potential applications of preclinica...

We demonstrate the generation of a highly polarized soft-x-ray beam with a compact high-repetition-rate tabletop soft-x-ray laser. The radiation emitted by a high-average-power discharge-pumped tabletop Ne-like Ar soft-x-ray laser operating at 46.9 nm was polarized with a pair of Si/Sc multilayer mirrors designed for 45° operation. A degree of polarization greater than 0.96 was obtained. The po...

The linewidth of a 14.7 nm wavelength Ni-like Pd soft x-ray laser was measured in a single shot using a soft x-ray diffraction grating interferometer. The instrument uses the time delay introduced by the gratings across the beam to measure the temporal coherence. The spectral linewidth of the 4d1S0-4p1P1 Ni-like Pd lasing line was measured to be Δλ/λ=3×10(-5) from the Fourier transform of the f...

We report mutimodal imaging findings of an extraskeletal chondroma of the Hoffa's fat pad. Plain radiographic or CT scan studies demonstrate a large soft tissue mass with calcifications and central ossification, characteristic features of these tumors. Magnetic resonance (MR) imaging shows heterogeneous signal due to polymorphic histopathological appearance. Correlation between MR imaging and p...