context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...

conclusions pivka-ii was as efficient as afp when used as a single marker for hcc screening and the combination of two biomarkers gave a better performance. results the sensitivity and specificity of pivka-ii were 74.6% and 67.8% at a cutoff of 40 mau/ml and 64.2% and 89.7% at a cutoff of 200 mau/ml. the sensitivity and specificity of afp were 76.7% and 65.0% at a cutoff of 20 ng/ml and 60.4% a...

background: peritoneal tuberculosis accounts 1-2% of all forms of tuberculosis. peritoneal tuberculosis is an important differential diagnosis for ovarian cancer in women with ascites, adnexal mass and elevated cancer antigen 125 (ca125) levels. we report a case of a 32- year -old woman with multiple miliary peritoneal deposits mimicking advanced ovarian carcinoma. case presentation: a 32-year-...

â  â  background esophageal squamous cell carcinoma (escc) is usually detected in advanced stages resulting in a very poor prognosis. early diagnoâ­sis needs identification of clinically relevant precancerous lesions which could become the target of screening and early treatment. our aim was to check whether esophagitis could serve as a relevant histological precursor of escc in northern iran. ...

ameloblastic carcinoma (ac) is a rare malignant epithelial odontogenic tumor that histologically retains the features of ameloblastic differentiation and exhibits cytological features of malignancy in the primary or recurrent tumor. it may develop within a preexisting ameloblastoma or arise de novo or from an odontogenic cyst. epidemiological evidence shows that human cancer is generally caused...

sebaceous carcinoma is a relatively rare cutaneous tumor that is most commonly derived from the sebaceous glands located in periorbital area. the extraocular occurrence of this tumor is very rare. we report a case of an 85 years old woman who presented with a slowly enlarging mass on the right temporal region. histological examination of the lesion revealed a malignant sebaceous carcinoma occur...

Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell carcinoma (SCC) which is usually found in oral cavity mucosa. Cutaneous verrucous carcinoma is a rare entity and in this paper we report a 43 years old man with VC superimposed on chronically inflamed skin of ileostomy site. Previously, he was operated to treat rectal adenocarcinoma and has had ileostomy for six mon...