The incidence of life-threatening disseminated Candida albicans infections is increasing in hospitalized patients, with fatalities as high as 60%. Death from disseminated candidiasis in a significant percentage of cases is due to fungal invasion of the kidney, leading to renal failure. Treatment of candidiasis is hampered by drug toxicity, the emergence of antifungal drug resistance and lack of...

following the first report of laryngeal small cell carcinoma in canada in 1972,only 82 cases of this cancer has been reported in the literature untill 2001.this cancer originates from laryngeal neuroendocrine cells.It,s clinical presentation consists of hoarseness,breathing difficulty:and cigarette smoking is the most important risk factor.this type of cancer is mostly presented after 50 years ...

BACKGROUND The purpose of this study was to evaluate the contribution of laryngeal intraoperative nerve monitoring (IONM) during thyroidectomy in predicting postoperative laryngeal mobility. METHODS Between 2009 and 2012, 127 patients underwent thyroidectomy, during which 216 recurrent laryngeal nerves were stimulated with suprathreshold stimulations. Laryngeal mobility was examined through d...

Laryngeal schwannomas are rare, benign tumors, most often arising from the superior laryngeal nerve. We describe a case of a 68-year-old female with a laryngeal schwannoma of the recurrent laryngeal nerve after traumatic injury. We postulate that trauma to the recurrent laryngeal nerve during thyroidectomy or thyroplasty incited growth of a nerve sheath tumor. This is the first reported case of...

We describe the phenomenon of waning of focal hepatic and/or splenic lesions on abdominal computed tomographic (CT) scan during neutropenia in patients with chronic disseminated candidiasis. After observation of the phenomenon in one patient, a total of five cases were prospectively monitored with serial CT scans. After the diagnosis of disseminated candidiasis, hepatic lesions decreased in siz...

Here, it is shown that immunoneutralization of p43, a virulence-associated immunomodulatory protein secreted by Candida albicans, is responsible for immunoprotection against candidiasis after spontaneous healing of mice inoculated with 10(6) C. albicans blastoconidia. p43 is produced by the pathogenic Candida blastoconidia, and neither immunoprotection nor immunoneutralization can be elicited b...

Tsai, Tung-Lung, Shyue-Yih Chang, Chin-Yin Ho, and Yu Ru Kou. Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats. J Appl Physiol 101: 328 –338, 2006; doi:10.1152/japplphysiol.00064.2006.—Laryngopharyngeal or gastroesophageal reflux is associated with laryngeal airway hyperreactivity (LAH), but neither t...

BACKGROUND AND OBJECTIVES Candidiasis is a common opportunistic infection in HIV-infected patients. The spectrum of Candida infection is diverse, starting from asymptomatic colonization to pathogenicforms. The low absolute CD4+ T-lymphocyte count has traditionally been cited as the greatest risk factor for the development of Oropharyngeal Candidiasis and current guidelines suggest increased ris...

Two cases of invasive candidiasis in intensive care patients are presented to illustrate the usefulness of detection of antibodies to Candida albicans germ tubes in the diagnosis of invasive candidiasis and in monitoring the efficacy of the antifungal treatment.

the laryngeal mask airway (lma) is an important addition to the anesthetist's equipments. however, its usage may involve some complications. we have encountered an unusual and potentially serious complication using this equipment. a 45-year old man underwent cataract surgery under general anesthesia. after the induction of anesthesia, a size 4 of the reusable classic lma was inserted without an...