Studies have demonstrated a relationship between mammographic texture and breast cancer risk. To date, texture analysis has been limited by tissue superimposition in mammography. Digital Breast Tomosynthesis (DBT) is a novel x-ray imaging modality in which 3D images of the breast are reconstructed from a limited number of source projections. Tomosynthesis alleviates the effect of tissue superim...

Female breast tissue is composed of variable proportions of fat and fibroglandular tissue, and in general, an increased ratio of fibroglandular tissue to fat corresponds to increased mammographic density. Studies suggest that mammographic density is an independent risk factor for breast cancer, and the sensitivity of mammography can be lower with heterogeneously dense or extremely dense breasts...

PURPOSE To (a) determine the performance of screening mammography, ultrasonography (US), and physical examination (PE); (b) analyze the influence of age, hormonal status, and breast density; (c) compare the size and stage of tumors detected with each modality; and (d) determine which modality or combination of modalities optimize cancer detection. MATERIALS AND METHODS A total of 11,130 asymp...

Background: Radiation-induced cardiac events and pneumonitis are the major late radiotherapy side effects. Methods: We explored differences in dose distribution between 3D CRT, IMRT VMAT 125 women with unilateral breast cancer. The various to tumor OARs were studied for left right sided irradiation. Results: Upon using CRT breasts lymph nodes, we observed a significant increase ipsilateral lung...

More high-risk women with breast cancer are identified using genetic testing at a younger age. These young women often opt for prophylactic surgery. Most patients are reluctant for extra donor-site scars besides infections and necrosis. In order to reduce these risks, a two-stage breast reconstruction technique is used for high-risk women with large or ptotic breasts. We presume that this proce...

Diffuse optical tomography (DOT) is a noninvasive, nonionizing imaging modality that uses near-infrared light to visualize optically relevant chromophores. A recently developed dynamic DOT imaging system enables the study of hemodynamic effects in the breast during a breath-hold. Dynamic DOT imaging was performed in a total of 21 subjects (age 54±10  years) including 3 healthy subjects and 18 s...

breast metastasis of ovarian carcinoma is rare. to date, only 39 cases have been reported in the english-language  literature  so  far.  we  are  herewith  reporting  a  primary  ovarian  papillary  serous  cyst adenocarcinoma metastasing to breast and epsilateral supraclavicular node in a 58 year old female asthe first case in our centre, located at north-east india.  the purpose of reporting ...

The current era is characterized by the rapidly increasing use of computer-aided diagnosis (CAD) systems in medical field. These need a variety datasets to help develop, evaluate, and compare their performances fairly. Physicians indicated that breast anatomy, especially dense ones, probability cancer tumor development, vary highly depending on race. Researchers reported risk factors are relate...

BACKGROUND While many studies have shown that hormones can influence background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI), only few have directly address the effect of radiotherapy. The purpose of this study was to evaluate the impact of radiotherapy on BPE in breast MRI. MATERIALS AND METHODS A retrospective search identified 62 women with unilateral breast can...

Radiologic breast density is one of the predictive factors for breast cancer and the extent of the density is directly related to postmenopause. However, some patients have dense breasts even during postmenopause. This condition may be explained by the genes that codify for the proteins involved in the biosynthesis, as well as the activity and metabolism of steroid hormones. They are polymorphi...