Although dual left anterior descending arteries are found in about 1% of the population, identification and localization these coronaries remains a challenge for cardiac surgeons throughout coronary artery bypass graft surgery. We present case (LAD) disease highlight techniques used identifying vessels.

Strategies for indirect myocardial revascularization in end stage ischemic coronary artery disease have been described and are still developing, including transmyocardial laser revascularization, ischemic preconditioning, low-energy shock wave therapy, or epicardial transplantation of latissimus dorsi muscle flap. All of them are intended to induce angiogenesis and generate neocollaterals to im...

Distant metastasis is the major cause of cancer-related deaths in patients with lung adenocarcinoma (LAD). Emerging evidence reveals that miRNA is critical for tumor metastasis. miR-214 expression has been associated with LAD progression. However, whether and how miR-214 is involved in the development and metastasis of LAD remain unaddressed. Here, we found that the expression of miR-214 was el...

Recently, the use of percutaneous coronary intervention (PCI) for treatment of coronary artery disease has progressively increased. A large number of simple stenoses in one or two coronary vessels can be treated by PCI. Therefore, the number of high-risk and severely diseased patients referred for coronary artery bypass grafting (CABG) has been relatively increasing. Coronary endarterectomy has...

A key requirement of a low-gravity screen-channel liquid acquisition device (LAD) is the need to retain 100% liquid in the channel in response to propellant outflow and spacecraft maneuvers. The point at which a screen-channel LAD ingests vapor is known as breakdown, and can be measured several different ways such as: visual observation of bubbles in the LAD channel outflow; a sudden change in ...

BACKGROUND Coronary flow reserve has been considered an important diagnostic index of the functional significance of coronary artery stenosis. With Doppler technique, it has been assessed as the ratio of hyperemic to basal coronary flow velocity (coronary flow velocity reserve [CFVR]) by invasive or semiinvasive methods with a Doppler catheter, a Doppler guide wire, and a transesophageal Dopple...

A 68‐year‐old male was diagnosed congenital pulmonary stenosis (PS) and unstable angina. He had a history of chronic obstructive pulmonary disease (COPD). Echocardiography revealed dilated pulmonary artery branch and severe valvular PS. Transvalvular peak systolic pressure gradient (PG) was 64 mmHg (1 mmHg = 0.133 KPa). Coronary angiography demonstrated 75% narrowing of left main coronary (LM),...

A 25-year-old Japanese female complaining chest oppression and palpitation was admitted to hospital under the presumptive diagnosis of ischemic heart disease (IHD), although no obvious underlying disease associated with IHD was detected. Coronary angiography showed stenosis at the proximal site of left anterior descending artery (LAD), with dilatation and tortuosity at the bifurcation of the fi...

Exercise-induced ST-segment elevation in leads V1 and/or aVL in the absence of anterior Q waves occurred in 46 of 190 patients (24%) who underwent 12-lead exercise electrocardiography with thallium-201 myocardial perfusion imaging and coronary arteriography. Significant left anterior descending coronary artery (LAD) disease was present in 38 of 46 patients (83%) with V1/aVL ST evaluation and in...

We previously demonstrated that expression of Notch-1 is associated with poor prognosis in lung adenocarcinoma (LAD) patients. The aim of this study is to reveal whether Notch-1 was associated with Taxanes-resistant LAD and, the underlying mechanisms. We collected 39 patients of advanced LAD treated with Taxanes and found that positive Notch-1 expression is closely related to LAD lymph node met...