The lacrimal gland is a functional part of the mucosal immune system and is populated by lymphoid cells that begin to appear early in neonatal development. To define the events controlling the accumulation of these cells, an in vitro adherence assay was used to investigate the interactions of lymphocyte populations with neonatal and adult lacrimal tissue. It was found that (1) lymphocytes adher...

Percutaneous drainage of the bile ducts is an established procedure for malignant obstructions, in which a histological diagnosis is often not obtained. We describe the biopsy technique of obstructive lesions through biliary drainage access, using a 7F endoscopic biopsy forceps, widely available; some are even reusable. This technique applies to lesions of the hepatic ducts, of the common hepat...

GP2 is a membrane-associated secretory protein originally identified in zymogen granules of pancreatic acinar cells. Recently, this glycoprotein has attracted attention as a marker substance of M cells of Peyer's patches and for its involvement in the selective uptake of pathological bacteria via M cells. When we stained the conjunctiva and tear ducts of mice using a GP2 antibody, all goblet ce...

ObjectiveRadiological and anatomical study of the Lacrimal apparatus system in one-humped camel of Iran (Camelus Dromedarius) DesignProspective study AnimalsFive heads (cut above the third cervical vertebra) of adult Dromedary camels' cadavers were collected from the slaughterhouse of the Najafabad area of Isfahan Province, Iran. ProceduresThe anatomy of the nasolacrimal duct of onehumped camel...

PURPOSE To test the feasibility of gene transfer into lacrimal gland tissue in primary culture, using different viral vectors. METHODS Lacrimal glands were dissected from adult Sabra rats and divided by pincers to 0.3-0.4 mm fragments. Tissue was maintained under primary organ culture conditions using the "raft" technique. The ability of three different viral vectors to conduct beta-galactosi...

PURPOSE To analyze the features of lacrimal drainage system obstruction confirmed during external dacryocystorhinostomy surgeries and report the surgical outcomes. METHODS We reviewed the medical records of a total of 769 cases who underwent external dacryocystorhinostomy for primary lacrimal drainage obstruction between 2005 and 2014. Data about detailed location and extent of obstruction we...

PURPOSE To investigate the osmotic water permeability of lacrimal gland (LG) duct epithelium by means of calculation of filtration permeability and to investigate LG ductal fluid secretion. METHODS Experiments were performed on isolated rabbit LG duct segments maintained in short-term culture. Osmotically determined fluid movement or fluid secretion into the closed intraluminal space of cultu...

Histological examination of 99 human lacrimal glands showed a relationship between atrophy of the secretory acini and secretory duct obstruction, ascending periductal fibrosis, and obliteration of the adjacent blood vessels caused by lymphocytic and polymorphonuclear inflammation. Investigation of the subgroups of the B lymphocytic series by immunohistochemistry did not show any statistical cha...

PURPOSE To assess the effectiveness of bicanalicular silicone intubation (SI) in acquired partial nasolacrimal duct (NLD) obstruction. DESIGN Retrospective nonrandomized case series METHODS 72 tear ducts from 53 patients with severe epiphora due to acquired partial NLD obstruction underwent bicanalicular SI. Mean age at intubation was 55.9 years. The silicone tubes were removed after, on av...