A bacterial strain is described in which the structural genes of the lac operon have been fused by deletion to the trp operon. It is shown that in this strain lac messenger RNA synthesis is controlled by the t?y regulatory gene. DNA-RNA hybridization studies show that a fraction of the lac messenger RNA is covalently linked to the tr2, messenger RNA. These results demonstrate that at least a fr...

Objectives: To clarify the optimal length of the antral cuff (LAC) in patients after pylorus-preserving gastrectomy (PPG), we investigated relationships between LAC and postgastrectomy disorder (PGD) such as postprandial abdominal fullness (PAF), and between LAC and gastric empting function (GEF) in PPG patients. Background: The main cause of PGD in PPG patients has been considered to be LAC. R...

BACKGROUND Base deficit (BD) is commonly used in the operating room (OR) as an endpoint of resuscitation. BD is used as a surrogate marker for the accumulation of lactic acid(Lac). However, the BD can be affected by large amounts of saline. METHODS We conducted a survey of anesthesiologists regarding the use of BD. We also studied the reliability of BD to determine the presence of hyperlactat...

The gene lac-1, encoding the enzyme laccase, is the best characterized of a number of genes in the chestnut blight fungus, Cryphonectria parasitica, that are repressed by hypoviruses, a group of virulence-attenuating mycoviruses. lac-1 has also been shown to be transcriptionally activated by low concentrations of the translational inhibitor cycloheximide (CHX) and by the immunosuppressant cyclo...

BACKGROUND PHD-finger domain protein 5A (PHF5A) is a highly conserved small transcriptional regulator also involved in pre-mRNA splicing; however, its biological functions and molecular mechanisms in non-small cell lung cancer (NSCLC) have not yet been investigated. The purpose of this study was to determine the functional relevance and therapeutic potential of PHF5A in lung adenocarcinoma (LAC...

AIM To compare the sensitivity of doxorubicin (DOX) sensitive and DOX-resistant MC-rhabdomyosarcoma (MC-RMS) cells to the action of lymphokine-activated cells (LAC). RESULTS In vitro investigations showed that LAC received from the fraction of adherent lymphocytes possess the highest activity against DOX-resistant tumor cells, and LAC from lymphocytes of total pool--against DOX-resistant tumo...

In contrast to the ribosomal RNA gene expression increasing with growth rate, transcription of the lac operon is downregulated by cell growth rate. In continuous culture, growth rate regulation of lac promoter was independent of carbon substrate used and its location on the chromosome. Since the lac operon is activated by cyclic adenosine monophosphate (cAMP), which decreases with increasing ce...

Background: Cultural issues are important for diagnostic validity between different countries; little has been addressed from Latin America and Caribbean countries (LAC). Objective: To identify LAC studies on culture-bound syndromes (CBS) and extract potential empirical evidence about Susto, Nervios and Ataques de Nervios. Methods: Search strategies were carried out in Medline, Embase, Lilacs, ...

We present a new well defined sample of BL Lac objects selected from the ROSAT All-Sky Survey (RASS). The sample consists of 39 objects with 35 forming a flux limited sample down to fX(0.5− 2.0 keV) = 8 · 10 ergs cm s, redshifts are known for 33 objects (and 31 of the complete sample). X-ray spectral properties were determined for each object individually with the RASS data. The luminosity func...

Competition for foreign direct investment (FDI) among developing countries has intensified in recent years. Using a sample of 68 developing countries across dif ferent regions, with data from 1975-2005, this paper investigates whether Latin America and the Caribbean (LAC) dif fers from non-LAC regions in regard to determinants of FDI; the evidence suggests that there are dif ferences. In partic...