The way in which multiple cell types organize themselves into a carefully sculpted, 3D labyrinth of vessels that regulate blood flow throughout the body has been a longstanding mystery. Clinicians familiar with congenital cardiovascular disease recognize how genetic variants and modest perturbations in this complex set of spatiotemporal interactions and stochastic processes can result in life-t...

This paper presents the castle in Castlevania: Symphony of the Night as a structure that sets out a pattern of movement for the player-character that is similar to that experienced by the treader of a classical labyrinth. Specifically, this pattern is one of turning back on oneself and it always derives its meaning from the context in which it is performed. For example, the meaning of Theseus s...

Self-assembly of surface phase domains is a promising route to fabricate stable nanometer-scale structures. This Letter reports a novel labyrinth structure of orthogonal nanoscale ribbons of Cu4Pb3 ordered-alloy on Cu(100) formed by electrochemical deposition. The labyrinth develops as loops of Cu4Pb3 ribbons elongate as closely spaced paired stripes. The structure is explained in terms of elas...

Mouse Glial Cells Missing a (mGCMa) belongs to a small family of transcription factors named after the prototypical GCM from Drosophila. mGCMa was expected to regulate gliogenesis, but instead found to be primarily expressed during development in trophoblasts of chorion and labyrinth. Its deletion causes abnormal placental labyrinth formation and results in embryonic lethality. Here we identify...

This experiment was performed as a part of of ampullae of the labyrinth were damaged. the series of the electron microscopic studies on (3) The dense body and multivesicular body vestibular apparatus. extremely resembling lysosome were observed. (1) The cells of ampullae of the labyrinth (4) There was evidence morphologically that which were damaged with Viomycin in various the onset of cell da...

We report the clinical and MR imaging findings in two African-American patients with manifestations of sickle cell disease affecting the inner ear. Both suffered sudden-onset sensorineural hearing loss and vestibular symptoms, and both had high labyrinthine signal on T1-weighted MR images attributed to labyrinthine hemorrhage. Follow-up studies of the first patient revealed a decrease in abnorm...

Abstract As part of an international cooperation the research team from Slovak University Technology is involved in development new radiation shielding experimental workplaces for code verification and demonstration principles. One these activities so called “Mini Labyrinth” experiment. It a simple neutron gamma benchmark, inspired by ALARM-CF-AIR-LAB-001 ICSBEP The STU Mini Labyrinth, as its n...

Mutations of SLC26A4 are the most common cause of the hearing loss associated with enlargement of the vestibular aqueduct. SLC26A4 encodes pendrin, an anion exchanger expressed in the cochlea, the vestibular labyrinth, and the endolymphatic sac of the inner ear. Slc26a4 mice, devoid of pendrin expression, develop an enlarged membranous labyrinth which leads to the failure to develop hearing, th...

Labyrinth weirs have not a straight crest in the perpendicular direction to the flow. The plan view of the weir consists of multiple and broken linear crests that cause the increase of its effective length. The advantages of this type of weirs are higher discharge capacity, easy aeration as well as low fluctuations of water surface at the weir upstream. This paper deals with the simulation of t...

We study a class of artificial neural networks in which a physics-like conservation law upon the activity of connected neurons is imposed at each time. We postulate that the modification of the network activities may be interpreted as a learning capability if a judicious conservation law is chosen. We illustrate our claim by modeling a rat behavior in a labyrinth: the exploration of the labyrin...