نتایج جستجو برای: l929 cell
تعداد نتایج: 1684380 فیلتر نتایج به سال:
Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for ne...
The effects of eleven 1,4-dihydropyridine derivatives (DHPs) used alone or together with prooxidant anticancer drug doxorubicin were examined on two cancer (HOS, HeLa) and two nonmalignant cell lines (HMEC, L929). Their effects on the cell growth (3H-thymidine incorporation) were compared with their antiradical activities (DPPH assay), using well-known DHP antioxidant diludine as a reference. T...
Objective. Molecular basis of wound healing process needs to further examined to determine the effective individual biological cues. The objective of this study was to investigate the wound closure, proliferation, and viability of L929 fibroblast when cultured with different concentration of soluble RGD peptid. Methods. RGD peptide was synthesized manually on solid phase. The percentage of heal...
Formocresol is common treatment in exposed pulp of primary teeth at caries, trauma and damaged with cavity preparation. Although, clinical and radiographic success and good clinical results are observed, dentistry societies are still searching for materials interchangeable with formocresol. Suab1 is a phytochemical agent that was selected because of its anti- bleeding effect. In this study, we ...
In this study we examined the protein expression profiles in X-irradiated L929 cells to get insight into how mammalian cells respond to radiation-induced cell damage. L929 cells were irradiated with the dose of 6 Gy and cell lysates were collected at different time intervals (20 min, 12, 24, 36, 48 and 72 h). The extracted proteins were separated by 2-DE and quantified using computerized image ...
Jaboticaba is a fruit from a native tree to Brazil, Plinia peruviana. Jaboticaba peels are an important source of antioxidant molecules such as phenolic compounds. This study aimed to evaluate in vitro the activity of a hydroalcoholic extract of jaboticaba fruit peels (HEJFP) in wound healing processes and antioxidant activity in murine fibroblasts (L929 cell line). HEJFP concentrations (0.5, 1...
Invasive bacteria can induce their own uptake and specify their intracellular localization; hence it is commonly assumed that proximate modulation of host cell transcription is not required for infection. However, bacteria can also modulate, directly or indirectly, the transcription of many host cell genes, whose role in the infection may be difficult to determine by global gene expression. Is ...
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