abstract       background and objectives: diabetes induced oxidative stress plays an important role in pathological damage to the heart and liver by increased production of extracellular matrix. it is thought that the use of medicinal plants, particularly portulaca oleracea. l and regular exercise are effective. the aim of this study was to evaluate the effects of portulaca oleracea. l consumpt...

background: hepatitis delta virus (hdv) is a subviral human pathogen that exploits host rna editing activity to produce two essential forms of the sole viral protein, hepatitis delta antigen (hdag). editing at the amber/w site of hdv antigenomic rna leads to the production of the large form (l-hdag), which is required for rna packaging. methods: in this study, pcr-based site-directed mutagenesi...

Protein molecules adopt a specific global 3D structure in order to carry out their biological function. To achieve this native state a newly formed protein molecule has to fold. The folding process and the final fold are both determined by the sequence of amino acids making up the protein chain. It is not currently possible to predict the conformation of the native state from the amino acid seq...

Low molecular size additives such as L-arginine and the redox compounds have been used both in the culturemedium and in vitro refolding to increase recombinant proteins production. Additives increase proteinrefolding and yield of active proteins by suppressing aggregate formation or enhancing refolding process.In this work, a comparative study was performed on refolding of rec...

conclusions salivary free and total sialic acid, and total protein were higher in the paan consumers compared to non-consumers. due to the carcinogenic effect of smokeless tobacco, measurement of these parameters in saliva may be useful in early detection of oral cancer. results the concentration of salivary free sialic acid (23.21 ± 18.98 mg/l) was significantly increased in paan consumers. th...

In the food-energy-water (FEW) nexus, livestock has a dominant place. It is generally considered as water, energy and land-intensive. Aquaculture could provide additional animal protein contribute to meeting food demand. However, aquaculture requires natural resources causes freshwater pollution due aquafeed, fertilizer, hormone use. This study assesses sustainability of using indicators water ...

A protein molecule adopts a specific 3D structure, necessary for its function in the cell, through a process of folding. Modelling the folding process and predicting the final fold from the unique amino acid sequence remain challenging problems. We have previously described the application of L-systems, parallel rewriting rules, to modelling protein folding using two complementary approaches: a...