background: bombesin shows high affinity for gastrin-releasing peptide (grp) receptors which over expressed on the cell surfaces of several human tumors particularly in prostate and breast cancers. the aim of this study was labeling of designed analogue with99mtc via hynic and tricine /edda and evaluation as potential targeted tumor scintigraphic agent.materials and methods: hynic-bombesin was ...

hemangioma of the rib is a rare benign vascular tumor. herein, we report a 63-year-old man presenting with hemangioma of the left sixth rib. an osteolytic eccentric expansive mass with calcification and focal cortical disruption was detected on chest computed tomography (ct). the mass showed low 2-deoxy-2-[18f]-fluoro-d-glucose (18f-fdg) avidity on positron emission tomography. the patient unde...

conclusions liver metastasis of neuroendocrine tumors in iran presents in a very similar manner as that seen in western countries. in about 89% of cases with liver-net, complete imaging, clinical, and pathological studies can help to identify the primary origin of the liver-net, which is very important in the patient’s management. results the most common primary site of metastatic gi-net to the...

in 1890, coley observed that cancer patients who developed infections had smaller tumors. from this, he developed coley’s toxin and treated tumors with injections of infectious materials. in 1960s,  mahaley used monoclonal antibodies to treat central nervous system(cns)  tumors, that research and clinical investigations in brain tumor immunotherapy became a serious undertaking. there are severa...

odontogenic myxoma (om) is an infiltrative benign bone tumor that occurs almost exclusively in the facial skeleton. the radiographic characteristics of odontogenic myxoma may produce several patterns, making diagnosis difficult. cone-beam computed tomography (cbct) may prove extremely useful in clarifying the intraosseous extent of the tumor and its effects on surrounding structures. here, we r...

desmoplastic ameloblastoma is a rare variant of ameloblastoma. up until now, less than 150 patients have been reported in the literature. we report a case of desmoplastic ameloblastoma in a 45-year-old female with a painless swelling in the left anterior maxillary region. fine needle aspiration yielded no fluid. periapical and panoramic radiographs as well as computer tomography scan showed a m...

gastrointestinal stromal tumors (gists) are rare and these tumors are mesenchymal tumors that develop in the wall of the gi tract. the aim of this study was to report a case with gist in pregnancy in western iran. a 39-year-old pregnant female (g5 p4) was admitted with a chief complaint of abdominal pain and epigastric fullness on 12 th april 2016. sonography showed gestational age of 15w+1d an...

background and importance: disk sequestration can be defined as a herniated disk with perforation of the fibrous ring (or outermost annulus fibrosus) and posterior longitudinal ligament with migration of the disk fragment to the epidural space. even after the introduction of high-resolution magnetic resonance imaging (mri), it is still frequently misinterpreted as neoplastic masses. unfortunate...

despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...

verrucous carcinoma is a unique clinical and pathological entity which has been recognised in the recent years. it is a variant of well-differentiated squamous cell carcinoma which may occur in the larynx; other anatomic locations such as: the oral cavity, anogenital region, and skin may be involved. it accounts for 1-2% of all laryngeal cancers. the clinical, histopathological and biologic fea...