نتایج جستجو برای: krebs cycle
تعداد نتایج: 276207 فیلتر نتایج به سال:
BACKGROUND Myocardial infarction (MI) is one of the leading causes of heart failure. An increasing body of evidence links alterations in cardiac metabolism and mitochondrial function with the progression of heart disease. The aim of this work was to, therefore, follow the in vivo mitochondrial metabolic alterations caused by MI, thereby allowing a greater understanding of the interplay between ...
The relative importance of oxidation through the Krebs cycle or of conversion to acetoacetate for the oxidation of fatty acids in liver is unknown. Attempts have been made to answer this question by studies of the products of the oxidation of fatty acids in particulate systems (l-7). In most of the experiments this process has required the presence not only of adenine nucleotides, magnesium ion...
The actual roles of the adenine nucleotides and activating factors such as the dicarboxylic acids of the Krebs cycle in the oxidation of fatty acids by broken cell preparations are unknown. Oxidation of the fatty acid (l-5) and the activating factor (6-8) leads to the synthesis of the phosphate bonds of adenosinetriphosphate.’ These facts have been difficult to demonstrate because of the rapid ...
In this study we addressed the function of the Krebs cycle to determine which enzyme(s) limits the availability of reduced nicotinamide adenine dinucleotide (NADH) for the respiratory chain under H(2)O(2)-induced oxidative stress, in intact isolated nerve terminals. The enzyme that was most vulnerable to inhibition by H(2)O(2) proved to be aconitase, being completely blocked at 50 microm H(2)O(...
The possible intermediary position of the plant acids in respiration and carbohydrate metabolism as indicated for some plant tissues, suggests that a similar situation may exist in fruit. Many fruits contain comparatively large amounts of various acids (8) and apparently have a very active acid metabolism, as shown by the changes in concentration which occur during growth, ripening and storage....
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