Abstract The aim of this Perspective is to start a discussion about the real usefulness more or less sophisticated catalytic systems for Knoevenagel reaction with malononitrile, that can take place under mild conditions without need catalyst. From sustainable viewpoint questions are: Is it useful increase rate already occurs conditions? spend resources and time in designing, characterizing real...

The one-pot, multi-component synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) by tandem Knoevenagel-Michael reaction of phenylhydrazine, ethyl acetoacetate and aldehydes in the presence of silica-bonded N-propylpiperazine sulfamic acid (SBPPSA) as a recyclable solid acid catalyst was reported. SBPPSA showed much the same efficiency when used in consecutive reaction runs.

A simple, efficient and environment-friendly procedure for the synthesis of 5-arylidene rhodanines derivatives via a Knoevenagel type reaction was developed using rhodanine, variety differently substituted aldehydes Na2SO3 as benign catalyst in ethanol. Selected were subjected to basic hydrolysis afford 2-mercapto-3-substituted-acrylic acids. The presence boronic acid group is well tolerated su...

Functionalized alkenes were successfully synthesized via a clean procedure in short time by using new recycled heterogeneous catalyst prepared from Moroccan oil shale, this is characterized different technics such XRD, BET-BJH, MEB-EDS, and TGA, before it’s has been used the Knoevenagel condensation between aldehydes active methylenes. The results showed that coupling with ultrasound irradiatio...

It is wise to mimic a bioinspired system design nanoreactor as catalyst containing multiple components for cascade reaction. Here, we report the uniform growth of well-dispersed nano-scale ZIF-8 crystals on pore walls 3DOM TiO2 via TEA-assisted crystallization process. The UV-vis spectra indicate that photosensitizer can extend visible-light absorption TiO2. obtained efficiently catalyze one-po...