Background: Hair dye poisoning, with main toxic component paraphenylene diamine, is a medical emergency. It is on increasing trend in developing countries due to wide availability and low cost of hair dyes. It carries a high mortality and does not have any specific antidote. Case Report:  Twenty three years old patient presented with breathelessness along with difficulty in speaking for...

objective(s):acute kidney injury (aki), a syndrome characterized by decreased glomerular filtration, occurs in every 1 of 5 hospitalized patients.  renal ischemia-reperfusion, one of the main causes of aki, is of particular importance in the setting of kidney transplantation. materials and methods: sixty male rats were divided into four groups including control, nephrectomy, sham surgery and re...

BACKGROUND Galectin-3 (Gal-3), a β-galactoside-binding lectin, is increased in kidney injury and its pharmacological blockade reduces renal damage in acute kidney injury, hyperaldosteronism or hypertensive nephropathy. We herein investigated the effects of pharmacological Gal-3 inhibition by modified citrus pectin (MCP) in early renal damage associated with obesity and aortic stenosis (AS). R...

OBJECTIVES Acute kidney injury is characterized by sudden and generally revertible renal function impairment involving inability to maintain homeostasis. In pediatrics, the main causes of acute kidney injury are sepsis, use of nephrotoxic drugs and renal ischemia in critically ill patients. The incidence of acute kidney injury in these patients ranges from 20 to 30%, resulting in increased morb...

INTRODUCTION: Elevated hemoglobin A1c levels in patients with diabetes mellitus have been known as a risk factor for acute kidney injury after coronary artery bypass grafting. However, the relationship between hemoglobin A1c levels in non-diabetics and acute kidney injury is under debate. We aimed to investigate the association of preoperative hemoglobin A1c levels with acute kidney injury in n...

background: two questions about diagnostic value of urinary neutrophil gelatin associated lipocalin (ungal) in detection of acute kidney injury (aki) in children have remained unanswered; first, which cut-off point of ungal has the highest value in detection of aki; and second when is the best time for measuring this biomarker in a patient? accordingly, the present study aimed to conduct a syst...

normal 0 false false false en-us x-none ar-sa background: contrast induced kidney injury is an acute renal dysfunction that is secondary to the administration of radio contrast media. the purpose of this study was to evaluate the levels of urotensin-ii (ut-ii) and endothelin-i (et-i) after contrast media administration in patients undergoing percutaneous coronary interventions. materials and me...

OBJECTIVE To evaluate the predictive value of the pediatric-modified Risk, Injury, Failure, Loss, End-stage renal disease criteria for disease course severity in patients with or without acute kidney injury admitted to a PICU. DESIGN Retrospective cohort study. SETTING A 12-bed PICU at a tertiary referral center in Southern Brazil. PATIENTS All patients admitted to the study unit over a 1...

Introduction: Acute kidney injury (AKI) has been known as a complex clinical complication in diabetic patients. The main cause of AKI is ischemia/reperfusion injury (IRI). This study was designed to investigate the protective effects of GABA on renal IRI in hyperglycemic female and male rats. Methods: Sixty STZ induced diabetic male and female Wistar rats were categorized in 10 groups (5 fem...