Different types of ionizing radiation produce different dependences of cancer risk on radiation dose/dose rate. Sparsely ionizing radiation (e.g. γ-rays) generally produces linear or upwardly curving dose responses at low doses, and the risk decreases when the dose rate is reduced (direct dose rate effect). Densely ionizing radiation (e.g. neutrons) often produces downwardly curving dose respon...

BACKGROUND ionizing radiation on the lens of the eye can produce a progressive cataract. Small cumulative doses, over a long time period, can produce adverse effects on the professional capabilities of health workers in the ionizing radiation zone. OBJECTIVES The aim of this study was to ascertain whether occupational exposure to low levels of ionizing radiation can cause an increase in preva...

Ionizing radiation is electromagnetic radiation that has sufficient energy to remove electrons from atoms. Ionization results in the production of negatively charged free electrons and positively charged ionized atoms. Ionizing radiation can be classified into two categories: photons (X-radiation and gamma radiation) and particles (alpha and beta particles and neutrons). Five types or sources o...

Introduction: With the rapid advancement of technology in today's world, the use of ionizing radiation and radioactive materials has been expanding significantly. The use of radioactive resources and equipment in medical sciences is increasing. Failure to observe safety precautions when working with radiation can have serious risks for employees, people, the environment and eve...

Introduction: Ionizing radiation in medical imaging is one of the dominant sources of exposure, and correct knowledge of radiation protection, affects staff safety behaviors during procedures. This study aimed to assess the radiation protection Knowledge, Attitude and Practice (KAP) amongst nuclear medicine centers' staff in Iran. Methods: To evaluate the...

Carcinogenic effects of ionizing radiation and benzo[a]pyrene-7,8-diol-9,10-epoxide (B[a]PDE), a major metabolite of benzo[a]pyrene (B[a]P), have been well demonstrated both in vitro and in vivo. Two-stage carcinogenesis results indicate that mouse skin is highly susceptible to both ionizing radiation and benzo[a]pyrene-7,8-diol-9,10epoxide (B[a]PDE), a major metabolite of benzo[a]pyrene (B[a]P...

Ionizing radiation induces a diverse spectrum of DNA lesions, including strand breaks and oxidized bases. In mammalian cells, ionizing radiation-induced lesions are targets of non-homologous end joining, homologous recombination, and base excision repair. In vitro assays show a potential involvement of DNA polymerase lambda in non-homologous end joining and base excision repair. In this study, ...

Introduction: Retinoblastoma (RB) is a malignant retinal tumor, which affects infants and children. This cancer happens through a mutation in the retinoblastoma tumor suppressor genes (RB1). Inactivation of RB1 has been observed in more than 97% of all retinoblastoma patients with mutations. In recent years, RB treatment has developed significantly. RBchr('39')s treatment methods can be one or ...

Objective: To discover the role of MCPH1 in the DNA double-strand damage induced by ionizing radiation and the relationship with H2AX in esophageal cancer cell ECA109. Methods: ECA109 cancer cells will be accepted 8 Gy 1 h after irradiation for protein extraction and immunofluorescence observed MCPH1 and H2AX protein expression and nuclear foci changes. Establish a stable low expression of H2AX...

By solving the time-dependent radiation transfer problem of stellar radiation through evolving superbubbles within a smoothly varying H I distribution, we have estimated the fraction of ionizing photons emitted by OB associations that escapes the H I disk of our Galaxy. We considered a coeval star-formation history and a Gaussian star-formation history with a time spread σt = 2 Myr. We find tha...