Department of Electrical Engineering Department of Electrical Engineering Virginia Polytechnic Institute and State University University of Newcastle Blacksburg, VA 24061 New South Wales, 2308 Australia n ABSTRACT v(k) = y(k) — z(k) + c.[y(k—i) — z(k—i)I i=l A perturbed error system is developed to de— (4) scribe the parameter and output error behaviors of -. n reduced—order application of adap...

External potassium (K) activates the inward rectifier ROMK (K(ir)1.1) by altering the pH gating of the channel. The present study examines this link between external K and internal pH sensitivity using both the two-electrode voltage clamp and the perfused, cut-open Xenopus oocyte preparation. Elevating extracellular K from 1 mM to 10 mM to 100 mM activated ROMK channels by shifting their appare...

The removal of noise from speech signals has applications ranging from speech enhancement for cellular communications, to front ends for speech recognition systems. A nonlinear time-domain method called dual extended Kalman filtering (DEKF) is presented for removing nonstationary and colored noise from speech. We further generalize the algorithm to perform the blind separation of two speech sig...

A DETAILED LOOK AT THE OMEGA-K ALGORITHM FOR PROCESSING SYNTHETIC APERTURE RADAR DATA Matthew A. Tolman Department of Electrical and Computer Engineering Master of Science In this thesis, the Omega-k algorithm used for processing stripmap synthetic aperture radar (SAR) data is explored in detail. While the original Omega-k algorithm does not achieve the same SNR as a matched filter, a modificat...

K(+) channels distinguish K(+) from Na(+) in the selectivity filter, which consists of four ion-binding sites (S1-S4, extracellular to intracellular) that are built mainly using the carbonyl oxygens from the protein backbone. In addition to ionic discrimination, the selectivity filter regulates the flow of ions across the membrane in a gating process referred to as C-type inactivation. A charac...

The ability of biological ion channels to conduct selected ions across cell membranes is critical for the survival of both animal and bacterial cells. Numerous investigations of ion selectivity have been conducted over more than 50 years, yet the mechanisms whereby the channels select certain ions and reject others are not well understood. Here we report a new application of Jarzynski's Equalit...