GoRLiN, R. J., VICKERS, R. A., KELLN, E., and WILLIAMSON, J. J., 'Multiple basal-cell nevi syndrome. An analysis of a syndrome consisting of multiple nevoid basal-celled carcinoma, jaw cysts, skeletal anomalies, medulloblastoma, and hyporesponsiveness to parathormone', Cancer, 1965, 18, 89. HOWELL, J. B., ANDERSON, D. E., and MCCLENDON, J. L., 'The basal cell nevus syndrome', J. Am. med. Ass., ...

Objectives The aim of the present study was to document the frequency and clinicopathologic features of intra-osseous jaw lesions in an Iranian pediatric population over a 20-year period. Methods Data were obtained from the archives of the Oral Pathology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran. The lesions were classified into four groups: (A) odontogenic cysts...

Primary intraosseous odontogenic squamous cell carcinoma (PIOSCC) is a rare tumor. The incidence is low, and approximately 200 cases are reported in literature. The etiology is associated with the malignant degeneration of embryological remains. Differential diagnosis includes alveolar carcinomas, jaw metastases from other locations, odontogenic tumors, and tumors of the maxillary sinus. Howeve...

BACKGROUND Odontogenic keratocysts (OKCs) now reclassified as Keratocystic odontogenic tumours (KCOTs) are a clinical entity with a characteristic microscopic picture, kinetic growth and biological behaviour. They arise from the proliferation of the epithelial dental lamina in both maxilla and mandible and occur in patients of all ages. 70-80% of keratocysts are found in the mandible commonly i...

INTRODUCTION Gorlin-Goltz syndrome is an uncommon hereditary condition caused by mutations in the PTCH1 gene causing a wide range of developmental abnormalities. Multiple basal cell carcinomas, palmoplantar pits and jaw cysts are cardinal features. Many clinicians are unfamiliar with the different manifestations and the fact that patients are especially sensitive to ionizing radiation. MATERI...

INTRODUCTION Nevoid basal cell carcinoma syndrome is a rare autosomal dominant disorder characterized by numerous basal cell carcinomas, odontogenic keratocysts of the jaws and developmental defects. The disorder results from mutations in the PTCH1 gene. CASE PRESENTATION A 15-year-old boy presented to our dental clinic with multiple jaw cysts. The patient had broad confluent eyebrows, a broa...

Context: Developmental odontogenic cysts account for 25% of all odontogenic cysts of the jaw. They are commonly associated with impacted or embedded teeth like mandibular/maxillary third molar and maxillary canines. Dentigerous cyst (DC) is a common developmental odontogenic cyst, but its inflammatory variant is quite rare. Settings and design: The representative tissue received was 10% formali...

KCOT is one of the most aggressive odontogenic cysts with a high recurrence rate, this was explained histopathologically as it typically shows a thin, friable wall, which is often difficult to enucleate from the bone in one piece, and have small satellite cysts within the fibrous wall. Multiple surgical approaches were introduced including decompression, marsupilization, enucleation with or wit...

INTRODUCTION Therapeutic approach to jaw cysts may depend on their dimensions and localization. Enucleation of cystic lesion is not always preferable in the first act, especially if large cysts are in close proximity to important anatomical structures. The aim of this paper was to present the outcome of the treatment protocol comprising preoperative decompression and subsequent enucleation of a...

A 9-year-old girl with a solid variant of an aneurysmal bone cyst in the 3rd lumbar vertebra showed a good response to low-dose radiation as the only treatment. The solid variant of aneurysmal bone cyst is thought to be a reactive response to intraosseous hemorrhage and is also called giant cell reparative granuloma or giant cell reaction. These lesions in the jaw and the short tubular bones of...