Pyroptosis is a type of programmed cell death that induces myocardial ischemia-reperfusion injury (I/RI), which leads to cardiac dysfunction and even lethal reperfusion injury. MiR-122 liver-specific miRNA associated with coronary heart disease, but its role in pyroptosis activation I/RI remains unclear. Thus, this study aimed determine whether miR-122 inhibition exerts protection vivo vitro mo...

PT. XYZ is a company engaged in the field of Automotive Parts Manufacturer. In carrying out its production this uses make to order. The carries simple planning and scheduling, namely FCFS (First Come First Serve). has problem, there no scheduling with appropriate machine assignment. This causes sometimes experience delays completing product. purpose study overcome problems companies minimize or...

Oxidative stress is thought to contribute to the initiation and progression of atherosclerosis. As glutathione peroxidase-1 (Gpx1) is an antioxidant enzyme that detoxifies lipid hydroperoxides, we tested the impact of Gpx1 deficiency on atherosclerotic processes and antioxidant enzyme expression in mice fed a high-fat diet (HFD). After 12 weeks of HFD, atherosclerotic lesions at the aortic sinu...

conclusions real-time pcr and elisa showed high levels of production of 1a/jfh1 chimeric hcv in the huh7.5 cell culture. the constructed virus can be used for future studies, including the development of new hcv drugs and vaccines. background the e2 glycoprotein is an important encoded hepatitis c virus (hcv) protein that contains three different variable regions. objectives the aim of the pres...

PCV173 Are SPAniSh regionS imPlementing the nAtionAl therAPeutiC PoSitioning rePort (tPr) regArding new orAl AntiCoAgulAntS (noAC) in the SAme wAy? A CASe of regionAl VAriAbility in drug ACCeSS Rodriguez Barrios JM1, Pérez-Alcántara F2, Gonzalez-Juantey JR3, Avendaño C4, Suarez C5, López-Bastida J6, Barja de Soroa P1 1Daiichi-Sankyo, Madrid, Spain, 2OBLIKUE Consulting, Barcelona, Spain, 3Santia...