BACKGROUND Human infestation to ectoparasites such as ticks, lice, cimex, fleas, mites and others agents may result in intensive allergic reaction with symptoms of itching, skin infection and severe irritation. In this case report, we present a case of dermatitis caused by cat flea. CASE PRESENTATION A three-member family referred to dermatology clinic in Babol due to dermal complications. Th...

Generalized pruritus is a distressing symptom that can occur in several dermatologic and systemic disorders. Generalized pruritus of unknown origin is that which affects patients without any underlying dermatologic or systemic disorder and is unassociated with rash. It most commonly occurs in older patients and persists for long periods, from months to years. In many cases, the itching may be d...

Progressive pigmentary purpura or Schamberg's disease. Pigmented purpuric lichenoid dermatitis of Gougerot and Blum red/brown papules and plaques in men which responds to psoralen combined with ultraviolet A (PUVA) treatment. Purpura annularis telangiectodes rare, with a preponderance in young females and manifests as annular erythematous plaques and patches. Eczematoid-like purpura of Doucas a...

BACKGROUND Alagille Syndrome is a rare genetic disease characterized by abnormalities of the intrahepatic biliary ducts with cholestasis along with multisystem anomalies. CASE CHARACTERISTICS An 8-year old child with persisting jaundice, severe itching and failure to thrive. OBSERVATION Diagnosis of Alagille syndrome was made on the basis of clinical features, typical facies and liver biops...

Case Report A 16-year-old boy presents to the allergy clinic with complaints of perioral itching and tingling after handling apples at his father’s fruit stall. He had experienced such symptoms on previous occasions, but this time he has developed mild lip swelling and tongue itching, as well. He has a history of seasonal allergic rhinitis that is controlled by nasal steroid spray. His father i...

BACKGROUND Altered kallikrein-related peptidase activity and bradykinin are associated with skin disorders in humans and mice under chronic inflammation conditions. The bradykinin B1 receptor (B1R), also known as one of the G-protein-coupled receptor family and usually absent in intact tissues and upregulated during tissue injury, is responsible for vasodilation, capillary permeability, nocicep...

Paroxysmal itching is described in three Japanese women with multiple sclerosis and previously reported cases are discussed. This paroxysmal symptom is rare, but may be the first and only symptom at the onset of multiple sclerosis.

Background: The footwear industry is a significant segment of leather in India. Workers shoe are exposed to mixtures organic solvents used for colouring, adhesion, cleaning and fumes which could lead respiratory skin problems. Objectives: To study allergic rhinitis symptoms examine lesions workers harmful agents industry. Methodology: It cross-sectional conducted November 2018 4 days among indu...

Facial follicular scales, dandruff, scalp itching and ocular alterations are lesser-known signs of rosacea demodicosis. The aim this prospective original study was to investigate the presence these symptoms in patients with almost-clear, mild moderate papulopustular differences between Demodex-positive Demodex-negative rosacea. Twenty-seven out 60 (45%) presented 24 (40%) involvement 22 (36.67%...