Salvia reuterana Bioss. is an aromatic perennial plant traditionally used for its anxiolytic and sedative properties. In the present study, various fractions and essential oil of S. reuterana aerial parts were investigated to find its free radical scavenging principles. Hydroalcoholic fraction with IC50 value of 112.6 ±3.2 μg ml-1 in DPPH assay demonstrated the highest free radical scavenging a...

(0.25 mg/liter), and CaCO3(7 g/liter). Air was sparged at 10 liter/minute; agitation was set at 500 rpm; temperature was maintained at 28°C; dissolved oxygen was set to 99.9% at 0 time. The whole mash was harvested after it was incubated for 4 days. The pellet obtained by centrifugation was extracted with methanol (6 liters) and the extract, upon concentration to a volume of 1 liter, was partit...

Shrimp is one of the most popular seafood items worldwide, and has been reported as a source of chemopreventive compounds. In this study, shrimp lipids were separated by solvent partition and further fractionated by semi-preparative RP-HPLC and finally by open column chromatography in order to obtain isolated antiproliferative compounds. Antiproliferative activity was assessed by inhibition of ...

Sumatranaxanthone A (1), a new xanthone, was isolated from the rot bark of Cratoxylum sumatranum. The structures were established based on spectroscopic studies, notably of the 1D and 2D NMR spectra. Preliminary results showed that 1 has antioxidative activity with inhibition 81% to fit with ascorbat acid standard.

A new cyclohexenone compound was isolated as a mixture of enantiomers from a culture filtrate of Lasiodiplodia theobromae. The relative structure was determined to be 4,5-dihydroxy-3-methyl-cyclohex-2-enone on the basis of MS, (1)H-NMR, and (13)C-NMR spectroscopic analyses, including 2D-NMR experiments. Resolution of the enantiomers was conducted by a coupling reaction with (S)-MTPA-Cl followed...

The ocean covers about 70% of the earth surface providing a diverse living environment for invertebrates [1]. Therefore, marine natural products will play a major role in drug discovery in the future. The work on marine natural products started 59 years ago when Bergman discovered the novel bioactive Arabino-nucleoside from marine sponge Cryptotethya crypta [2]. This discovery encouraged natura...

ABSTRACT. This study was designed to investigate the chemical constituents from Actinodaphne pruinosa growing in Malaysia. A phytochemical investigation of leaves part resulted isolation boldine (1), norboldine (2), laurotetanine (3), reticuline (4), syringaresinol (5), lupeol (6), and taraxerol (7). The structures isolated phytochemicals were established by analysis their spectroscopic data, a...