In the title compound, C30H31N3O2S, the fused pyrrolidine ring bearing three substituents adopts an envelope conformation with the C atom bearing the benzoyl group as the flap. The other fused pyrrolidine ring adopts a twisted conformation about one of its C-C bonds. The dihedral angle between the isatin ring system and the methyl-thia-zole ring is 25.95 (8)°. An intra-molecular C-H⋯O inter-act...

An organocatalytic asymmetric allylation of 3-indolylmethanol has been established via hydrogen-bond activating mode, which directly assembles isatin-derived 3-indolylmethanols and o-hydroxystyrenes into chiral allyl-substituted oxindoles with one all-carbon quaternary stereogenic center and one newly formed C=C bond in excellent enantioselectivity and (Z)-selectivity (up to 97% ee, >20 : 1 Z/E...

The aim of the present study is to synthesize the oxovanadium complex of the V3+ ion with isatin sciff bases. Spectroscopic methods have been used to confirm these models of complexation and to understand the structures of the species formed in methanolic solution. We also have isolated a complex of Vanadium (III) with isatin schiff bases in the solid phase.

A simple and straightforward synthetic approach to potential anti-infective thiolactone-isatin hybrids led to the discovery of novel tetracyclic compounds which bear a macrocylic motif containing an unusual bridged amide bond.

In the title compound, C(16)H(13)N(5)O(3)S·CH(4)O, the dihedral angle between the isatin unit and the 2-methyl-phenyl group is 41.81 (2)° and intra-molecular N-H⋯O and N-H⋯N hydrogen bonds occur, generating S(6) and S(5) rings, respectively. In the crystal, polymeric chains arise as a result of N-H⋯O, O-H⋯S and C-H⋯O inter-actions.

Fe-MIL-101-isatin-Schiff-base-Co was synthesized and applied as a catalyst for Ullmann-type, Buchwald–Hartwig, Hirao, Hiyama Mizoroki–Heck cross-coupling reactions of aryl halides.

Diazonium chlorides of 5-amino-3-methypyrazole 1a and 5-amino-4-phenylpyrazole 1b coupled with 1,3-indanedione 2 and led to the formation of acyclic hydrazone 3a and a cyclic product indenopyrazolotriazine 4b respectively. Cyclization of the hydrazone 3a by boiling in acetic acid afforded the corresponding 4a. The hydrazone 3a reacted with malononitrile in boiling ethanol in the presence of pip...

The title compound, C(19)H(18)N(4)O(3) [systematic name: (RS)-1-benzyl-3-hy-droxy-3-(2-imino-3-methyl-5-oxoimidazolidin-4-yl)-2,3-dihydro-1H-indol-2-one], was prepared as a racemate (RR and SS) by the aldol condensation of N-benzyl-isatin with creatinine in the presence of sodium acetate in acetic acid. The r.m.s. deviation of the isatin ring system is 0.033 Å. The benzyl group is disordered ov...