Eight cases of pellagra, diagnosed on the grounds of neuropathological findings and retrospective study of clinical data, were found among 106 necropsy cases of tuberculosis. Although these eight patients had shown various mental, neurological and gastrointestinal symptoms, as well as skin lesions, the diagnosis of pellagra had not been made clinically. In all the patients, pellagra symptoms ap...

Permanent Brooke ileostomy continues to be a treatment option for selected patients with inflammatory bowel disease and cancer. This case report describes the author’s 50-year experience living Crohn’s ileostomy, including psychosocial dietary adaptations required management of common complications such as peri-stomal irritant dermatitis, food blockage, acute infectious diarrhea. Cross-sectiona...

This is a case report on irritant contact dermatitis secondary to calcium oxide exposure during manual cloud seeding operations. A less hazardous substitute such as sodium chloride should be considered wherever possible. Cloud seeding operations are briefly discussed in this report, and the impact of calcium oxide exposure as an occupational hazard is elaborated.

Cancer treatment with epidermal growth factor receptor inhibitors (EGFRIs) often induces severe xerotic dermatitis. Various irritants facilitate development of dermatitis in skin. As zinc deficiency plays a role the irritant dermatitis, we measured serum levels 25 patients due to EGFRIs. Of these patients, nine were treated EGFR tyrosine kinase and 16 anti-EGFR antibody alone or combination oth...

After more than a decade of use, topical minoxidil solution has proven to be a safe and effective treatment for androgenetic alopecia. However, some patients present with complaints of pruritus and scaling of the scalp. The most common causes of these symptoms include irritant contact dermatitis, allergic contact dermatitis, or an exacerbation of seborrheic dermatitis. Patients suffering from a...

Over the past years, hydrocolloid dressings have been introduced routinely in the treatment of various types of wounds. They provide a moist environment promoting autolytic debridement, and stimulate angiogenesis. However, long-term application often leads to inflammation of the skin in the immediate area of the ulcer, causing irritant dermatitis in many cases, but sometimes also leads to conta...

Metalworking fluids (MWFs) are a common cause of allergic and irritant contact dermatitis. MWFs being currently used are mostly water based, containing biocides, emulsifiers, and other additives. We performed a retrospective analysis of the etiology of the occupational dermatoses caused by metalworking fluids in three regions of Central Slovakia (population of approximately 2 million) between 2...

Irritant or allergic contact dermatitis usually presents as an eczematous process, clinically characterized by erythematoedematovesicous lesions with intense itching in the acute phase. Such manifestations become erythematous-scaly as the condition progresses to the subacute phase and papular-hyperkeratotic in the chronic phase. Not infrequently, however, contact dermatitis presents with nonecz...

BACKGROUND In the last two years several cases of severe contact dermatitis related to newly acquired sofas and armchairs originating from China have been published. The responsible allergen is dimethylfumarate (DMF), an extremely potent sensitizer and irritant found in sachets inside the furniture. Recently, cases of contact dermatitis related to shoes and riding helmets have also been describ...

BACKGROUND Plastics are a common cause of occupational skin disorders such as irritant or allergic contact dermatitis (ACD). CASE REPORT We report a case of occupational ACD due to a polyvinyl chloride (PVC) plastic table cover used as a mouse pad for which we performed patch tests and obtained positive patch tests for the PVC table cover. Composition testing revealed the presence of phthalat...