Central to embryonic development is the generation of molecular asymmetries across fields of undifferentiated cells. The Drosophila wing imaginal disc provides a powerful system with which to understand how such asymmetries are generated and how they contribute to formation of a complex structure. Early in development, the wing primordium is subdivided into a thin layer of peripodial epithelium...

There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.

aortic dissection occurs when a tear develops in the wall of the aorta, which is rare in the young population. this fatal disorder is hard to diagnose, especially in young patients. we present the case of aortic dissection in a 15-year-old boy referred to the emergency department of yazd university of medical sciences in november 2015. the patient presented to our department with sudden acute c...

S ports participation during childhood, adolescence, and the teenage years is the focus of much attention by a variety of pediatric stakeholders. The physical, mental, and emotional development associated with athletic endeavors can play a great dividend in adulthood. Whether it is a team sport demanding the combined effort of various personalities and skills sets or the mental toughness requir...

Many English noun pairs suggest an almost limitless array of semantic interpretation. A fruit bowl might be described as a bowl for fruit, a bowl that contains fruit, a bowl for holding fruit, or even (perhaps in a modern sculpture class), a bowl made out of fruit. These interpretations vary in syntax, semantic denotation, plausibility, and level of semantic detail. For example, a headache pill...

The elucidation of pathways linking patterning to morphogenesis is a problem of great interest. We show here that, in addition to their roles in patterning and morphogenesis of the hindgut, the Drosophila genes drumstick (drm) and bowl are required in the foregut for spatially localized gene expression and the morphogenetic processes that form the proventriculus. drm and bowl belong to a family...

CONTEXT Recent studies support the hypothesis that postinfectious irritable bowel syndrome and some irritable bowel syndrome patients display persistent signs of minor mucosal inflammation. Mesalazine has intestinal anti-inflammatory properties including cyclooxygenase and prostaglandin inhibition. The effects of mesalazine on postinfectious irritable bowel syndrome and noninfective irritable b...

INTRODUCTION Pigmented villonodular synovitis (PVNS) is a proliferative condition of the synovium, which is composed of nodules and/or villi and has an abundant number of hemosiderin-laden macrophages. CASE REPORT A 10-year-old boy presented with an acute irritable knee. Emergency arthroscopy showed a nodular PVNS in the intercondylar notch. The symptoms resolved after resection of the lesion...

We really read with a great interest the paper by Durakoğlugil et al. (1) entitled “The effect of irritable bowel syndrome on carotid intimamedia thickness, pulse wave velocity, and heart rate variability” published in the September issue of Anatol J Cardiol 2014; 14: 525-30. They purposed to investigate a possible association between irritable bowel syndrome and autonomic dysfunction using hea...