نتایج جستجو برای: ipi

تعداد نتایج: 1246  

2017
Honyin Chiu Sharmila Mallya Phuongthao Nguyen Annie Mai Leandra V. Jackson David G. Winkler Jonathan P. DiNitto Erin E. Brophy Karen McGovern Jeffery L. Kutok David A. Fruman

The class I phosphoinoside-3-kinases (PI3Ks) are important enzymes that relay signals from cell surface receptors to downstream mediators driving cellular functions. Elevated PI3K signaling is found in B cell malignancies and lymphocytes of patients with autoimmune disease. The p110δ catalytic isoform of PI3K is a rational target since it is critical for B lymphocyte development, survival, acti...

Journal: :Blood 2008
Eva Hoster Martin Dreyling Wolfram Klapper Christian Gisselbrecht Achiel van Hoof Hanneke C Kluin-Nelemans Michael Pfreundschuh Marcel Reiser Bernd Metzner Hermann Einsele Norma Peter Wolfram Jung Bernhard Wörmann Wolf-Dieter Ludwig Ulrich Dührsen Hartmut Eimermacher Hannes Wandt Joerg Hasford Wolfgang Hiddemann Michael Unterhalt

There is no generally established prognostic index for patients with mantle cell lymphoma (MCL), because the International Prognostic Index (IPI) and Follicular Lymphoma International Prognostic Index (FLIPI) have been developed for diffuse large cell and follicular lymphoma patients, respectively. Using data of 455 advanced stage MCL patients treated within 3 clinical trials, we examined the p...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Laura R de Baaij Johannes Berkhof Jolanda M W van de Water Michal K Sieniawski Marijn Radersma Wieke H M Verbeek Otto J Visser Joost J Oudejans Chris J L M Meijer Chris J J Mulder Anne L Lennard Saskia A G M Cillessen

PURPOSE Enteropathy-associated T-cell lymphoma (EATL) is a rare intestinal non-Hodgkin lymphoma with a poor, though variable prognosis. The International Prognostic Index (IPI) and the prognostic index for peripheral T-cell lymphoma (PIT) have limited predictive value for outcome of EATL. The purpose of this study was to develop and validate a prognostic model for EATL, which can identify high-...

2008
Soo Jung Park Shin Kim Dae Ho Lee Yong Pil Jeong Yunjeong Bae Eun Mee Han Jooryung Huh Cheolwon Suh

PURPOSE Anaplastic large cell lymphoma (ALCL), a CD30+ T-cell non-Hodgkin's lymphoma, represents only 2-8% of lymphoma overall. Information on the clinical findings of primary systemic ALCL in Korea is limited. Our aims were to report the clinical features and outcomes of primary systemic ALCL. PATIENTS AND METHODS We retrospectively reviewed the medical records of 36 adult patients diagnosed...

2011
Johannes Griss María Martín Claire O'Donovan Rolf Apweiler Henning Hermjakob Juan Antonio Vizcaíno

The International Protein Index (IPI) database has been one of the most widely used protein databases in MS proteomics approaches. Recently, the closure of IPI in September 2011 was announced. Its recommended replacement is the new UniProt Knowledgebase (UniProtKB) "complete proteome" sets, launched in May 2011. Here, we analyze the consequences of IPI's discontinuation for human and mouse data...

Journal: :Iranian journal of veterinary research 2016
S S Abu-Akkada S S Oda

This study was conducted to evaluate the efficacy of oral administration of fenbendazole (20 mg/kg body weight) prior to and after experimental infection of immunosuppressed rabbits with Encephalitozoon cuniculi. A total of thirty rabbits were divided into five groups: NN (non-immunosuppressed; non-infected), IN (immunosuppressed; non-infected), IPI (immunosuppressed; protected-infected), ITI (...

Journal: :Telaah Bisnis 2021

Penelitian ini bertujuan untuk mengetahui pengaruh inflasi, Indeks Produksi Industri (IPI) dan kurs terhadap penghimpunan zakat, infaq sedekah (ZIS) di BAZNAS tahun 2014-2018 menggunakan Autoregressive Distributed Lag (ARDL), hasil penelitian menunjukkan bahwa hanya variabel IPI yang berpengaruh signifikan dana ZIS. Sedangkan Inflasi tidak signifikan. Namun, semua memiliki kointegrasi jangka pa...

2011
Silvia Y. Bando Maryana C. Alegro Edson Amaro Alexandre V. Silva Luiz H. M. Castro Hung-Tzu Wen Leandro de A. Lima Helena Brentani Carlos Alberto Moreira-Filho

BACKGROUND Prolonged febrile seizures constitute an initial precipitating injury (IPI) commonly associated with refractory mesial temporal lobe epilepsy (RMTLE). In order to investigate IPI influence on the transcriptional phenotype underlying RMTLE we comparatively analyzed the transcriptomic signatures of CA3 explants surgically obtained from RMTLE patients with (FS) or without (NFS) febrile ...

Journal: :Pediatrics 2011
Keely Cheslack-Postava Kayuet Liu Peter S Bearman

OBJECTIVE To determine whether the interpregnancy interval (IPI) is associated with the risk of autism in subsequent births. METHODS Pairs of first- and second-born singleton full siblings were identified from all California births that occurred from 1992 to 2002 using birth records, and autism diagnoses were identified by using linked records of the California Department of Developmental Ser...

Journal: :Blood 1997
R Ristamäki H Joensuu K Lappalainen L Teerenhovi S Jalkanen

CD44 molecule is a cell surface glycoprotein involved in many cell-cell and cell-matrix interactions. Circulating serum CD44 (s-CD44) levels have been found to change in parallel with response to therapy, but little is known about the predictive or prognostic significance of s-CD44. In the present study, we measured s-CD44 levels in sera taken before treatment from 194 patients with non-Hodgkin...

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