BACKGROUND Heavy-ion therapy has an advantage over conventional radiotherapy due to its superb biological effectiveness and dose conformity in cancer therapy. It could be a potential alternate approach for hydatid cyst treatment. However, there is no information currently available on the cellular and molecular basis for heavy-ion irradiation induced cell death in cystic echinococcosis. METHO...

Ionizing radiation is a universal tool in tumor therapy but may also cause secondary cancers or cell invasiveness. These negative side effects could be causally related to the human-intermediate-conductance Ca2+-activated-K+-channel (hIK), which is activated by X-ray irradiation and affects cell proliferation and migration. To analyze the signaling cascade downstream of ionizing radiation we us...

Health effects caused by ionizing radiations raise considerable concern among general public and radiation workers. To estimate ability of personal protective equipment (PPE) materials that reduce toxic effects of ionizing radiations, we developed an experimental bioassay system using Chinese Hamster V79 cells. The system developed here distinguished the biological effectiveness of X-ray that w...

Many studies suggest that exogenous antioxidants may protect cells against DNA damage caused with ionizing radiation. One of the most powerful antioxidants is lycopene (LYC), a carotenoid derived from tomatoes. The aim of this study was to investigate, using the comet assay, whether LYC can act as protectors/modifiers and prevent DNA damage induced in human blood lymphocytes, as well as to miti...

The last two decades have witnessed increasing use of X-ray imaging and, hence, the exposure humans to potentially harmful ionizing radiation. Computed tomography accounts for largest portion medically-related exposure. Accurate knowledge radiation dose from Cone-Beam CT (CBCT) is great importance estimate risks and justification exposures. This work aimed review published evidence on CBCT esti...

Introduction: Medical workers in the departments of radiology, computed tomography, nuclear medicine, and radiotherapy are always exposed to ionizing radiations. Complete blood count (CBC) test is commonly used to monitor the health of radiation workers. The aim of this study was to evaluate the hematological parameters of radiation workers of Isfahan, Iran, and reveal...

Ionizing radiation has been successfully used in medical tests and treatment therapies for a variety of medical conditions. However, patients and health-care workers are greatly concerned about overexposure to medical ionizing radiation and possible cancer induction due to frequent mammographies and/or CT scans. Diagnostic imaging involves the use of low doses of ionizing radiation, and its pot...

Screening mammography offers the possibility of discovering malignant diseases at an early stage, which is consequently treated early, thereby reducing the mortality rate. However, ionizing radiation as used in low-dose X-ray mammography may be associated with a risk of radiation-induced carcinogenesis. In the context of the harmful effects of ionizing radiation, this article reviewed novel rad...

2. Ionizing radiation Individual types of IR possess different biological effectiveness. In order to it unit of equivalent dose was defined – 1 Sievert (Sv). Equivalent dose represents absorbed dose multiplied with factor connected with biological effectiveness of IR. More precisely, this factor expresses how many times is precise IR effective than photons of X or gamma radiation (röentgen radi...