A new plastic membrane ion-selective electrode for determination of metformin hydrochloride has been prepared, after forming the ion pair of metformin hydrochloride with sodium tetraphenylborate. Dioctyl phthalate and sodium tetraphenylborate were used as plasticizer and counter ion respectively. The electrode exhibited a linear potential response in the concentration range 1 × 10 M–1 × 10 M wi...

Polymer-supported liquid-crystal membranes have been designed for neutral-carrier-type potassium ion-selective electrodes, aiming for practical applications of high-performance liquid-crystalline membrane ion sensors. Two types of polymer-supported liquid-crystal membranes were tested for their usefulness; one is microporous poly(tetra fluoroethylene) (PTFE) membranes impregnated by thermotropi...

N-Alkyltheobromine (1-9) derivatives were obtained by reacting theobromine with appropriate alkyl halide under microwave irradiation at 100-150 W and by conventional synthesis. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were considered. The presented compounds 1-5 have been studied as ion carriers in ion-selective membrane electrodes. Selectivity of...

Determining the effective concentration (i.e., activity) of ions in and around living cells is important to our understanding of the contribution of those ions to cellular function. Moreover, monitoring changes in ion activities in and around cells is informative about the actions of the transporters and/or channels operating in the cell membrane. The activity of an ion can be measured using a ...

Detecting warfarin levels in the blood is of critical importance anticoagulant therapy because it imperative that concentration drug maintained within a specific range. In this paper, we present proof-of-concept novel sensing device based on ion-selective electrode (ISE) technology for direct detection samples without any sample pretreatment. We used tetradodecylammonium chloride (TDDA) as an i...

In recent years, the use of ion-selective membranes in sensing and assessment environmental contaminants has become a critical goal. Using sodium tetraphenylborate (TPB) phosphotungstic acid (PTA) as ion-pairing agents, two sensitive selective sensors were manufactured to evaluate electrochemical response moxifloxacin hydrochloride (MOX). The optimal behavior was attained by fine-tuning all ass...

Ionic rectifier membranes or devices generate uni-directional ion transport to convert an alternating current (AC) input into stored energy direct (DC) in the form of ion/salt gradients. Electrochemical experiments 80 years ago were conducted on biological membrane systems, but today a plethora artificial ionic types has been developed and electroanalytical tools are employed explore mechanisms...