Background: During the aging process, muscle atrophy and neuromuscular junction remodeling are inevitable. The present study aimed to clarify whether low-intensity aerobic exercise along with limb blood-flow restriction (BFR) could improve aging-induced muscle atrophy and nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction.Methods: Forty-eight male Wistar rats, aged 23–24 m...

purpose: microgravity causes major changes in various systems of the body in space, such as shift in cerebrospinal fluid, decreased red blood cells count, and electrolyte loss. these complications are very important in space and we should find new approaches to prevent the side effects of microgravity in astronauts. materials and methods: this experimental study was conducted on 21 adult male r...

Objective To examine the efficacy and safety of combination therapy with exenatide plus pioglitazone vs basal/bolus insulin in patients with poorly controlled type 2 diabetes mellitus (T2DM) with very high hemoglobin A1c (HbA1c) (>10%) receiving sulfonylurea plus metformin and with a long duration of disease. Design and Participants Participants (n = 101) in the Qatar Study with very poor gly...

introduction: various hemostatic and analgesic agents and techniques have been used to reduce intraoperative and postoperative hemorrhage and pain in tonsillectomy.aims and objective; the current study aimed to compare the effect of using adrenaline plus tramadol and normal saline in maintaining hemostasis and control of pain in cold dissection tonsillectomy.   materials and methods: this prosp...

in order to study the response of wheat (triticum aestivum) cv. chamran and wild barley (hordeum spontaneum) to different herbicides, a pot dose response experiment was conducted in a completely randomized design with three replication at research greenhouse of ferdowsi university of mashhad in 2008. different doses of herbicides including clodinafop propargyl, pinoxaden, sulfosulfuron, and met...

The aim of this study was to investigate the effects of various doses of essential oils (EO) of thyme (TEO) or cinnamon (CEO) on in vitro rumen degradation of protein of a commercial total mixed ratio (TMR) containing 16.4% crud protein (CP). Treatments were TMR without any of EOs (control); control plus 25 µL of TEO (TEO25); control plus 50 µL of TEO (TEO50); control plus 25 µL of CEO (CEO25) ...

INTRODUCTION Real-world comparative effectiveness, safety, and supportive care use of nab-paclitaxel plus carboplatin vs gemcitabine plus platinum were analyzed in patients with advanced or metastatic squamous cell non-small cell lung cancer (NSCLC). MATERIALS AND METHODS Patients who received ≥ 1 cycle of first-line nab-paclitaxel plus carboplatin or gemcitabine plus platinum were identified...