Background and objectives: Thyroid hormone exercises vital role in the event of development of central nervous system in stage of fetal life, childhood, and maintains tropic action in adulthood and also in aging. Deficiency in thyroid hormones responsible for impairment of mental performance. Inadequate iodine intake was is the major health problem. Use of iodized salt is now in vogue globally ...

Sodium Iodide-131 is administrated for treatment of hyperthyroidism and thyroid cancer. Iodine-131 has multiple routs of excretion (Urine, saliva, sweat, milk, feces, exhalation) from the body. Patients receiving Sodium Iodide-131 therapy exposes other persons and the environment to unwanted radiation and contamination. The major source of radiation dose from administration of Iodine-131 ...

We have evaluated the electric characteristics of an organic surfactant material, n-Cethyl-trimethyl-ammonium Bromide (C16TAB) to fabricate the p-n homo-junction. This C16TAB was dissolved in the pure water, where the potassium iodide (KI) was added. The impurities adaptation has been processed in this mixed solution with the application of voltage. The KI is ionized in the water and the potass...

PURPOSE Iodine, bivalent iron (Fe²⁺), and hydrogen peroxide (H₂O₂), all significantly affecting the red-ox balance, are required for thyroid hormone synthesis. Intracellular iodine excess (≥10⁻³ M) transiently blocks thyroid hormonogenesis (an adaptive mechanism called Wolff-Chaikoff effect). The aim of the study was to evaluate the effects of iodine, used as potassium iodide (KI) or potassium ...

Brown algae of the Laminariales (kelps) are the strongest accumulators of iodine among living organisms. They represent a major pump in the global biogeochemical cycle of iodine and, in particular, the major source of iodocarbons in the coastal atmosphere. Nevertheless, the chemical state and biological significance of accumulated iodine have remained unknown to this date. Using x-ray absorptio...

CONTEXT Perchlorate has been detected in U.S. drinking water supplies at levels ranging from 4 to 200 microg/liter as well as in agricultural products. Perchlorate is known to be a competitive inhibitor of iodine uptake by the thyroid through the sodium-iodide symporter. OBJECTIVE The objective of the study was to determine whether prolonged exposure (6 months) to low levels of perchlorate wo...

Iodine preparations for external use are recommended for treating pressure ulcers with manifestations of infection and necrosis. These ulcers abundantly produce wound exudates, which could be absorbed by water-soluble base. In this study we aimed to improve the previously reported methodologies for water absorption and new methodologies were developed in Franz diffusion cell with 100kDa molecul...

The role played in thyroid hormonogenesis by iodide oxidation to iodine (organification) is well established. Iodine deficiency may produce conditions of oxidative stress with high TSH producing a level of H_2O_2, which because of lack of iodide is not being used to form thyroid hormones. The cytotoxic actions of excess iodide in thyroid cells may depend on the formation of free radicals and ca...

The goal of the present investigation was to analyze the types 2 (D2) and 3 (D3) iodothyronine deiodinases in various structures within the central nervous system (CNS) in response to iodine deficiency. After 5-6 wk of low-iodine diet (LID) or LID + 2 microg potassium iodide/ml (LID + KI; control), rats' brains were processed for in situ hybridization histochemistry for D2 and D3 mRNA or dissec...

It is the present acceptance in general that the level of dietary iodine is of paramount importance for the proper working of the thyroid gland. Remington low iodine diet is much used for studies on iodine deficiency in rats. This diet induces the hyperactive state of the thyroid gland, which is proved by the increase of I131 uptake and thyroid/serum radioiodide concentration ratio(T/S ratio)or...