An emerging group of human genetic diseases termed 'ciliopathies' are caused by dysfunction of two functionally and physically associated organelles, the centrosome and cilium. These organelles are central to perception of the physical environment through detection of a diverse variety of extracellular signals such as growth factors, chemicals, light and fluid flow. Many of the described ciliop...

Background: Young people’s compliance with carriage of adrenaline auto-injectors (AAI) may be as low as 41%, yet we lack research exploring their preferences regarding these devices. Objective: This qualitative study explored young people’s ideas about AAI design and features which may facilitate their carriage and use. Methods: Young people aged 13-18 years prescribed an AAI for severe allergi...

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is associated with severe skin eruptions, fever, hematological abnormalities, and multi-organ involvement. Although aromatic anticonvulsant drugs have been frequently associated with the manifestation of DRESS syndrome, its induction following treatment with nonaromatic anticonvulsants, such as valproate, has rarely been rep...

H1N1 virus is known to affect the respiratory tract. The majority of healthcare providers focus on the respiratory complications attributed to H1N1 infection, overlooking possible multi-organ involvement. We present a rare case of abnormal liver function in a child who was admitted for respiratory illness due to the H1N1 virus. There was a marked elevation in liver function tests concurrent wit...

background: tuberculosis of the larynx is a rare form of tuberculosis. patients usually present with hoarseness or dysphagia and other nonspecific constitutional symptoms like fever or localized pain. in this study, we present a case of primary vocal cord lesion with tuberculosis. case presentation: a 72 year old man presented with hoarseness of voice, low grade fever, and night sweating with i...

Background: Kawasaki disease (KD) is one of the most prevalent vasculitis diseases in children and can bring about serious cardiovascular complications. Early detection of cardiac involvement in KD can play an essential role in managing and preventing the cardiac sequels. We aimed to evaluate the applicability and diagnostic accuracy of cardiac biomarkers including car...

The present research was conducted with the aim of exposition of the relationship between organizational climate and job involvement among teachers of high schools in Delijan city of Iran in year (2012-2013). The research was applied, descriptive and correlational.Statistical population included184 teachers in the first semester of educational year (2012- 2013), of which 125 teachers were selec...