نتایج جستجو برای: intraperitoneal route

تعداد نتایج: 85775  

Journal: :The Journal of Experimental Medicine 1940
Jonas E. Salk G. I. Lavin Thomas Francis

A study of the antigenic potency of influenza virus inactivated by ultraviolet radiation has been made. Virus so inactivated is still capable of functioning as an immunizing agent when given to mice by the intraperitoneal route. In high concentrations inactivated virus appears to be nearly as effective as active virus but when quantitative comparisons of the immunity induced by different diluti...

Journal: :Environmental Health Perspectives 1973
C Ramel

Background We attempted to determine the maximum tolerated dose and toxicity of etoposide (VP-16) when administered in combination with carboplatin (CBDCA) (300 mg m-2) and administered via the intraperitoneal (IP) route. Methods and Materials A total of 26 patients were treated on this trial. CBDCA was administered at a fixed dose of 300 mg m-2) while VP-16 was started at a dose of 200 mg m2 a...

Journal: :The Japanese journal of veterinary research 1999
A Takada K Okazaki H Kida

Intranasal administration of plasmid DNA encoding glycoprotein B of pseudorabies virus into mice induced both serum and secretory antibody responses. These mice resisted intranasal challenge with lethal dose of the virus, but did not intraperitoneal challenge. On the other hand, intramuscular injection of the plasmid induced less secretory and higher serum antibody responses than those of intra...

2013
Seema Singh

Purpose: The aim of the present study was to investigate the diuretic activity of ethanolic extracts and its fractions of Aegle marmelos fruit in experimental models. Ethanolic extracts and its fractions of Aegle marmelos ripe fruit were administered to experimental rats intraperitonealy at doses of 300, 400 and 500 mg/kg i. p. Control group received only normal saline (25ml/kg) through intrape...

2011
S. H. ESLAMI M. A. EBRAHIMZADEH A. HAJIZADEH MOGHADDAM S. F. NABAVI N. JAFARI S. M. NABAVI B. Eslami

Recent studies show that hydrogen peroxide free radicals have an important role in the renal damage induced by Gentamicin. Previously we studied the hydrogen peroxide scavenging activity of Eryngium caucasicum. This work was conducted to evaluate the possible renoprotective effect of Eryngium caucasicum against Gentamicin-induced renotoxicity. Extracts at the doses 200 and 400 mg/kg/day for 10 ...

Journal: :iranian journal of veterinary research 2007
s. hajighahramani n. vesal

the objective of this study was to evaluate several drug combinations for intraperitoneal anaesthesia in laboratory rats. following dose determination of anaesthetics in a pilot study, 45 healthy adult male rats were randomly assigned in 9 treatment groups and received propofol (alone or in combination with xylazine, midazolam, or ketamine) or ketamine (in combination with xylazine, midazolam, ...

Abbas Khadem Sameni Elahe Taghiabadi Hossein Hosseinzadeh, Saied Sadeghi Shakib

The acute and sub-acute toxicity of safranal were studied in rat and mice within 2 and 21 days after exposure, respectively. For subacute toxicity, changes in weight as well as biochemical, hematological and pathological parameters were studied. The intraperitoneal LD50 values of safranal were 1.48 mL/kg in male mice, 1.88 mL/kg in female mice and 1.50 mL/kg in male rats. Oral LD50 values were ...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007
Wynne K Schiffer Martine M Mirrione Stephen L Dewey

UNLABELLED Small-animal PET provides the opportunity to image brain activation during behavioral tasks in animal models of human conditions. The present studies aimed to simplify behavioral imaging procedures without a loss of quantitation by using an intraperitoneal route of administration (no cannulation, no anesthesia) and using a standardized uptake value (SUV) to reduce scan duration. ME...

J. M. Kaul M. Zirak Javanmard, R. Sadrkhanlou S. Hasanzadeh

Arsenic is an important environmental toxicant which is usually found in drinking water in inorganic form. The hypothesis tested in this investigation is; arsenic exposure causes neural tube defects (NTDs) andthese defects of the central nervous system are more likely related to folate deficiency during fetal life. In this study, sodium arsenate was administered via intraperitoneal route at a r...

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