Bornaviruses are nonsegmented negative-strand RNA viruses that establish a persistent infection in the nucleus and occasionally integrate a DNA genome copy into the host chromosomal DNA. However, how these viruses achieve intranuclear infection remains unclear. We show that Borna disease virus (BDV), a mammalian bornavirus, closely associates with the cellular chromosome to ensure intranuclear ...

Intranuclear inclusions were found in bone marrow cells of miniature pigs, whose ultrastructure and nature were examined by electron microscope and by cytochemical techniques. The inclusions were found predominantly in the granulocyte series and in a megakaryocyte and plasma cell. The inclusions consisted of closely packed, wavy filaments, 20-40 in number. They varied in size from 0.5-1.0 mum i...

The existence of intranuclear lipid-dependent signal transduction systems has been demonstrated by several independent groups. Remarkably, intranuclear lipid-dependent signal transduction pathways are regulated independently from their membrane/cytosolic counterparts. A sizable body of evidence suggests that nuclear lipid signaling controls critical biological functions such as cell proliferati...

In part 1 of this study, it was discussed that dental occlusion/temporomandibular joint (TMJ) status is functionally connected to general body health. The purpose of this part of the study was to attempt to formulate a conceptual account, the "fascial connection theory for TMJ and other parts of the body," to explain the functional connection between TMJ and other parts of the body. The first h...

We reported earlier that β-cell-specific overexpression of glutathione peroxidase (GPx)-1 significantly ameliorated hyperglycemia in diabetic db/db mice and prevented glucotoxicity-induced deterioration of β-cell mass and function. We have now ascertained whether early treatment of Zucker diabetic fatty (ZDF) rats with ebselen, an oral GPx mimetic, will prevent β-cell deterioration. No other an...

Objective: To report a case of iatrogenic central retinal artery occlusion after embolization and surgical resection of carotid body paraganglioma. Methods: Case report Results: One adult female patient presented with persistent unilateral visual loss after embolization with Embosphere® and Contour® microparticles of carotid body tumor. Fluorescein angiography revealed intraluminal microspheres...

Removal of a foreign body in the pulmonary circulation is typically attempted by an endovascular approach as first attempt. The artery must be occluded either manually or with cardiopulmonary bypass during procedure. Here, we report case video-assisted thoracic surgery to remove from right under percutaneous balloon occlusion. For difficult cases, can retrieved (VATS) Intravenous catheterizatio...

Accurate human posture estimation from single or multiple images is essential in many applications. Two main causes of difficulty to solve the estimation problem are large number of degrees of freedom and self-occlusion. Treestructured graphical models with efficient inference algorithms have been used to solve the problem in a lower dimensional state space. However, such models are not accurat...